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A New Class of 1-Aryl-5,6-dihydropyrrolo[2,1-a]isoquinoline Derivatives as Reversers of P-Glycoprotein-Mediated Multidrug Resistance in Tumor Cells.
Nevskaya AA, Matveeva MD, Borisova TN, Niso M, Colabufo NA, Boccarelli A, Purgatorio R, de Candia M, Cellamare S, Voskressensky LG, Altomare CD. Nevskaya AA, et al. Among authors: cellamare s. ChemMedChem. 2018 Aug 10;13(15):1588-1596. doi: 10.1002/cmdc.201800177. Epub 2018 Jul 4. ChemMedChem. 2018. PMID: 29802687
Scouting around 1,2,3,4-Tetrahydrochromeno[3,2-c]pyridin-10-ones for Single- and Multitarget Ligands Directed towards Relevant Alzheimer's Targets.
Purgatorio R, Kulikova LN, Pisani L, Catto M, de Candia M, Carrieri A, Cellamare S, De Palma A, Beloglazkin AA, Reza Raesi G, Voskressensky LG, Altomare CD. Purgatorio R, et al. Among authors: cellamare s. ChemMedChem. 2020 Oct 19;15(20):1947-1955. doi: 10.1002/cmdc.202000468. Epub 2020 Sep 4. ChemMedChem. 2020. PMID: 32716595
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding.
Tardia P, Stefanachi A, Niso M, Stolfa DA, Mangiatordi GF, Alberga D, Nicolotti O, Lattanzi G, Carotti A, Leonetti F, Perrone R, Berardi F, Azzariti A, Colabufo NA, Cellamare S. Tardia P, et al. Among authors: cellamare s. J Med Chem. 2014 Aug 14;57(15):6403-18. doi: 10.1021/jm500697c. Epub 2014 Aug 5. J Med Chem. 2014. PMID: 25093931
Design, synthesis, biological evaluation, NMR and DFT studies of structurally simplified trimethoxy benzamides as selective P-glycoprotein inhibitors: the role of molecular flatness.
Stefanachi A, Mangiatordi GF, Tardia P, Alberga D, Leonetti F, Niso M, Colabufo NA, Adamo C, Nicolotti O, Cellamare S. Stefanachi A, et al. Among authors: cellamare s. Chem Biol Drug Des. 2016 Dec;88(6):820-831. doi: 10.1111/cbdd.12811. Epub 2016 Jul 26. Chem Biol Drug Des. 2016. PMID: 27331911
77 results