Ceckova M - Search Results

1

Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy.

Sorf A, Vagiannis D, Ahmed F, Hofman J, Ceckova M. Sorf A, et al. Among authors: ceckova m. Toxicol Appl Pharmacol. 2022 Jan 1;434:115797. doi: 10.1016/j.taap.2021.115797. Epub 2021 Nov 13. Toxicol Appl Pharmacol. 2022. PMID: 34780725

2

Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro.

Sorf A, Hofman J, Kučera R, Staud F, Ceckova M. Sorf A, et al. Among authors: ceckova m. Biochem Pharmacol. 2018 Aug;154:10-17. doi: 10.1016/j.bcp.2018.04.013. Epub 2018 Apr 16. Biochem Pharmacol. 2018. PMID: 29673999

3

Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters.

Sorf A, Novotna E, Hofman J, Morell A, Staud F, Wsol V, Ceckova M. Sorf A, et al. Among authors: ceckova m. Biochem Pharmacol. 2019 May;163:290-298. doi: 10.1016/j.bcp.2019.02.035. Epub 2019 Feb 28. Biochem Pharmacol. 2019. PMID: 30826329

4

Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance.

Hofman J, Sorf A, Vagiannis D, Sucha S, Novotna E, Kammerer S, Küpper JH, Ceckova M, Staud F. Hofman J, et al. Among authors: ceckova m. Drug Metab Dispos. 2019 Jul;47(7):699-709. doi: 10.1124/dmd.119.086975. Epub 2019 May 8. Drug Metab Dispos. 2019. PMID: 31068367

5

Brivanib Exhibits Potential for Pharmacokinetic Drug-Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter and CYP450 Biotransformation Enzymes.

Hofman J, Sorf A, Vagiannis D, Sucha S, Kammerer S, Küpper JH, Chen S, Guo L, Ceckova M, Staud F. Hofman J, et al. Among authors: ceckova m. Mol Pharm. 2019 Nov 4;16(11):4436-4450. doi: 10.1021/acs.molpharmaceut.9b00361. Epub 2019 Oct 21. Mol Pharm. 2019. PMID: 31633365

6

ABCB1 as a potential beneficial target of midostaurin in acute myeloid leukemia.

Sucha S, Sorf A, Svoren M, Vagiannis D, Ahmed F, Visek B, Ceckova M. Sucha S, et al. Among authors: ceckova m. Biomed Pharmacother. 2022 Jun;150:112962. doi: 10.1016/j.biopha.2022.112962. Epub 2022 Apr 21. Biomed Pharmacother. 2022. PMID: 35462331 Free article.

7

Transplacental pharmacokinetics of glyburide, rhodamine 123, and BODIPY FL prazosin: effect of drug efflux transporters and lipid solubility.

Cygalova LH, Hofman J, Ceckova M, Staud F. Cygalova LH, et al. Among authors: ceckova m. J Pharmacol Exp Ther. 2009 Dec;331(3):1118-25. doi: 10.1124/jpet.109.160564. Epub 2009 Sep 24. J Pharmacol Exp Ther. 2009. PMID: 19779128

8

Olomoucine II and purvalanol A inhibit ABCG2 transporter in vitro and in situ and synergistically potentiate cytostatic effect of mitoxantrone.

Hofman J, Ahmadimoghaddam D, Hahnova L, Pavek P, Ceckova M, Staud F. Hofman J, et al. Among authors: ceckova m. Pharmacol Res. 2012 Mar;65(3):312-9. doi: 10.1016/j.phrs.2011.11.017. Epub 2011 Dec 6. Pharmacol Res. 2012. PMID: 22173067

9

Olomoucine II, but not purvalanol A, is transported by breast cancer resistance protein (ABCG2) and P-glycoprotein (ABCB1).

Hofman J, Kučera R, Cihalova D, Klimes J, Ceckova M, Staud F. Hofman J, et al. Among authors: ceckova m. PLoS One. 2013 Oct 8;8(10):e75520. doi: 10.1371/journal.pone.0075520. eCollection 2013. PLoS One. 2013. PMID: 24116053 Free PMC article.

10

Purvalanol A, olomoucine II and roscovitine inhibit ABCB1 transporter and synergistically potentiate cytotoxic effects of daunorubicin in vitro.

Cihalova D, Hofman J, Ceckova M, Staud F. Cihalova D, et al. Among authors: ceckova m. PLoS One. 2013 Dec 23;8(12):e83467. doi: 10.1371/journal.pone.0083467. eCollection 2013. PLoS One. 2013. PMID: 24376706 Free PMC article.

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