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Ambra1 modulates the tumor immune microenvironment and response to PD-1 blockade in melanoma.
Frias A, Di Leo L, Antoranz A, Nazerai L, Carretta M, Bodemeyer V, Pagliuca C, Dahl C, Claps G, Mandelli GE, Andhari MD, Pacheco MP, Sauter T, Robert C, Guldberg P, Madsen DH, Cecconi F, Bosisio FM, De Zio D. Frias A, et al. Among authors: cecconi f. J Immunother Cancer. 2023 Mar;11(3):e006389. doi: 10.1136/jitc-2022-006389. J Immunother Cancer. 2023. PMID: 36868570 Free PMC article.
Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy.
Strappazzon F, Vietri-Rudan M, Campello S, Nazio F, Florenzano F, Fimia GM, Piacentini M, Levine B, Cecconi F. Strappazzon F, et al. Among authors: cecconi f. EMBO J. 2011 Apr 6;30(7):1195-208. doi: 10.1038/emboj.2011.49. Epub 2011 Feb 25. EMBO J. 2011. PMID: 21358617 Free PMC article.
Apaf1 plays a pro-survival role by regulating centrosome morphology and function.
Ferraro E, Pesaresi MG, De Zio D, Cencioni MT, Gortat A, Cozzolino M, Berghella L, Salvatore AM, Oettinghaus B, Scorrano L, Pérez-Payà E, Cecconi F. Ferraro E, et al. Among authors: cecconi f. J Cell Sci. 2011 Oct 15;124(Pt 20):3450-63. doi: 10.1242/jcs.086298. Epub 2011 Oct 7. J Cell Sci. 2011. PMID: 21984814 Free article.
New insights into the link between DNA damage and apoptosis.
De Zio D, Cianfanelli V, Cecconi F. De Zio D, et al. Among authors: cecconi f. Antioxid Redox Signal. 2013 Aug 20;19(6):559-71. doi: 10.1089/ars.2012.4938. Epub 2012 Nov 9. Antioxid Redox Signal. 2013. PMID: 23025416 Free PMC article. Review.
AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation.
Cianfanelli V, Fuoco C, Lorente M, Salazar M, Quondamatteo F, Gherardini PF, De Zio D, Nazio F, Antonioli M, D'Orazio M, Skobo T, Bordi M, Rohde M, Dalla Valle L, Helmer-Citterich M, Gretzmeier C, Dengjel J, Fimia GM, Piacentini M, Di Bartolomeo S, Velasco G, Cecconi F. Cianfanelli V, et al. Among authors: cecconi f. Nat Cell Biol. 2015 Jan;17(1):20-30. doi: 10.1038/ncb3072. Epub 2014 Dec 1. Nat Cell Biol. 2015. PMID: 25438055 Free PMC article.
312 results