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Inhibition of Eicosanoid Degradation Mitigates Fibrosis of the Heart.
Rubino M, Travers JG, Headrick AL, Enyart BT, Lemieux ME, Cavasin MA, Schwisow JA, Hardy EJ, Kaltenbacher KJ, Felisbino MB, Jonas E, Ambardekar AV, Bristow MR, Koch KA, McKinsey TA. Rubino M, et al. Among authors: cavasin ma. Circ Res. 2023 Jan 6;132(1):10-29. doi: 10.1161/CIRCRESAHA.122.321475. Epub 2022 Dec 8. Circ Res. 2023. PMID: 36475698 Free article.
Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation.
Stratton MS, Bagchi RA, Felisbino MB, Hirsch RA, Smith HE, Riching AS, Enyart BY, Koch KA, Cavasin MA, Alexanian M, Song K, Qi J, Lemieux ME, Srivastava D, Lam MPY, Haldar SM, Lin CY, McKinsey TA. Stratton MS, et al. Among authors: cavasin ma. Circ Res. 2019 Sep 13;125(7):662-677. doi: 10.1161/CIRCRESAHA.119.315125. Epub 2019 Aug 14. Circ Res. 2019. PMID: 31409188 Free PMC article.
Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism.
Cavasin MA, Demos-Davies K, Horn TR, Walker LA, Lemon DD, Birdsey N, Weiser-Evans MC, Harral J, Irwin DC, Anwar A, Yeager ME, Li M, Watson PA, Nemenoff RA, Buttrick PM, Stenmark KR, McKinsey TA. Cavasin MA, et al. Circ Res. 2012 Mar 2;110(5):739-48. doi: 10.1161/CIRCRESAHA.111.258426. Epub 2012 Jan 26. Circ Res. 2012. PMID: 22282194 Free PMC article.
HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling.
Travers JG, Wennersten SA, Peña B, Bagchi RA, Smith HE, Hirsch RA, Vanderlinden LA, Lin YH, Dobrinskikh E, Demos-Davies KM, Cavasin MA, Mestroni L, Steinkühler C, Lin CY, Houser SR, Woulfe KC, Lam MPY, McKinsey TA. Travers JG, et al. Among authors: cavasin ma. Circulation. 2021 May 11;143(19):1874-1890. doi: 10.1161/CIRCULATIONAHA.120.046462. Epub 2021 Mar 8. Circulation. 2021. PMID: 33682427 Free PMC article.
HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Lin YH, Major JL, Liebner T, Hourani Z, Travers JG, Wennersten SA, Haefner KR, Cavasin MA, Wilson CE, Jeong MY, Han Y, Gotthardt M, Ferguson SK, Ambardekar AV, Lam MP, Choudhary C, Granzier HL, Woulfe KC, McKinsey TA. Lin YH, et al. Among authors: cavasin ma. J Clin Invest. 2022 May 16;132(10):e148333. doi: 10.1172/JCI148333. J Clin Invest. 2022. PMID: 35575093 Free PMC article.
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy.
Ferguson BS, Wennersten SA, Demos-Davies KM, Rubino M, Robinson EL, Cavasin MA, Stratton MS, Kidger AM, Hu T, Keyse SM, McKnight RA, Lane RH, Nozik ES, Weiser-Evans MCM, McKinsey TA. Ferguson BS, et al. Among authors: cavasin ma. Am J Physiol Heart Circ Physiol. 2021 Aug 1;321(2):H382-H389. doi: 10.1152/ajpheart.00115.2021. Epub 2021 Jun 18. Am J Physiol Heart Circ Physiol. 2021. PMID: 34142888 Free PMC article.
Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism.
Jeong MY, Lin YH, Wennersten SA, Demos-Davies KM, Cavasin MA, Mahaffey JH, Monzani V, Saripalli C, Mascagni P, Reece TB, Ambardekar AV, Granzier HL, Dinarello CA, McKinsey TA. Jeong MY, et al. Among authors: cavasin ma. Sci Transl Med. 2018 Feb 7;10(427):eaao0144. doi: 10.1126/scitranslmed.aao0144. Sci Transl Med. 2018. PMID: 29437146 Free PMC article.
41 results