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Phenylbutyrate rescues the transport defect of the Sec61α mutations V67G and T185A for renin.
Sicking M, Živná M, Bhadra P, Barešová V, Tirincsi A, Hadzibeganovic D, Hodaňová K, Vyleťal P, Sovová J, Jedličková I, Jung M, Bell T, Helms V, Bleyer AJ, Kmoch S, Cavalié A, Lang S. Sicking M, et al. Among authors: cavalie a. Life Sci Alliance. 2022 Jan 21;5(4):e202101150. doi: 10.26508/lsa.202101150. Print 2022 Apr. Life Sci Alliance. 2022. PMID: 35064074 Free PMC article.
Protein transport into the human endoplasmic reticulum.
Dudek J, Pfeffer S, Lee PH, Jung M, Cavalié A, Helms V, Förster F, Zimmermann R. Dudek J, et al. Among authors: cavalie a. J Mol Biol. 2015 Mar 27;427(6 Pt A):1159-75. doi: 10.1016/j.jmb.2014.06.011. Epub 2014 Jun 23. J Mol Biol. 2015. PMID: 24968227 Review.
An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases.
Lang S, Pfeffer S, Lee PH, Cavalié A, Helms V, Förster F, Zimmermann R. Lang S, et al. Among authors: cavalie a. Front Physiol. 2017 Nov 1;8:887. doi: 10.3389/fphys.2017.00887. eCollection 2017. Front Physiol. 2017. PMID: 29163222 Free PMC article. Review.
Sec61 complexes form ubiquitous ER Ca2+ leak channels.
Lang S, Erdmann F, Jung M, Wagner R, Cavalie A, Zimmermann R. Lang S, et al. Among authors: cavalie a. Channels (Austin). 2011 May-Jun;5(3):228-35. doi: 10.4161/chan.5.3.15314. Epub 2011 May 1. Channels (Austin). 2011. PMID: 21406962
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER.
Schäuble N, Lang S, Jung M, Cappel S, Schorr S, Ulucan Ö, Linxweiler J, Dudek J, Blum R, Helms V, Paton AW, Paton JC, Cavalié A, Zimmermann R. Schäuble N, et al. Among authors: cavalie a. EMBO J. 2012 Aug 1;31(15):3282-96. doi: 10.1038/emboj.2012.189. Epub 2012 Jul 13. EMBO J. 2012. PMID: 22796945 Free PMC article.
Identification of signal peptide features for substrate specificity in human Sec62/Sec63-dependent ER protein import.
Schorr S, Nguyen D, Haßdenteufel S, Nagaraj N, Cavalié A, Greiner M, Weissgerber P, Loi M, Paton AW, Paton JC, Molinari M, Förster F, Dudek J, Lang S, Helms V, Zimmermann R. Schorr S, et al. Among authors: cavalie a. FEBS J. 2020 Nov;287(21):4612-4640. doi: 10.1111/febs.15274. Epub 2020 Mar 20. FEBS J. 2020. PMID: 32133789 Free article.
63 results