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Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential.
Martinez DR, Moreira FR, Zweigart MR, Gully KL, De la Cruz G, Brown AJ, Adams LE, Catanzaro N, Yount B, Baric TJ, Mallory ML, Conrad H, May SR, Dong S, Scobey DT, Montgomery SA, Perry J, Babusis D, Barrett KT, Nguyen AH, Nguyen AQ, Kalla R, Bannister R, Bilello JP, Feng JY, Cihlar T, Baric RS, Mackman RL, Schäfer A, Sheahan TP. Martinez DR, et al. Among authors: catanzaro n. bioRxiv [Preprint]. 2023 Jun 28:2023.06.27.546784. doi: 10.1101/2023.06.27.546784. bioRxiv. 2023. PMID: 37425890 Free PMC article. Preprint.
Human ACE2 expression, a major tropism determinant for SARS-CoV-2, is regulated by upstream and intragenic elements.
Snouwaert JN, Jania LA, Nguyen T, Martinez DR, Schäfer A, Catanzaro NJ, Gully KL, Baric RS, Heise M, Ferris MT, Anderson E, Pressey K, Dillard JA, Taft-Benz S, Baxter VK, Ting JP, Koller BH. Snouwaert JN, et al. Among authors: catanzaro nj. PLoS Pathog. 2023 Feb 22;19(2):e1011168. doi: 10.1371/journal.ppat.1011168. eCollection 2023 Feb. PLoS Pathog. 2023. PMID: 36812267 Free PMC article.
Vaccine-mediated protection against merbecovirus and sarbecovirus challenge in mice.
Martinez DR, Schafer A, Gavitt TD, Mallory ML, Lee E, Catanzaro NJ, Chen H, Gully K, Scobey T, Korategere P, Brown A, Smith L, Parks R, Barr M, Newman A, Bowman C, Powers JM, Mansouri K, Edwards RJ, Baric RS, Haynes BF, Saunders KO. Martinez DR, et al. bioRxiv [Preprint]. 2023 May 23:2023.05.22.540829. doi: 10.1101/2023.05.22.540829. bioRxiv. 2023. PMID: 37293083 Free PMC article. Updated. Preprint.
Host genetic variation guides hepacivirus clearance, chronicity, and liver fibrosis in mice.
Brown AJ, Won JJ, Wolfisberg R, Fahnøe U, Catanzaro N, West A, Moreira FR, Nogueira Batista M, Ferris MT, Linnertz CL, Leist SR, Nguyen C, De la Cruz G, Midkiff BR, Xia Y, Evangelista MD, Montgomery SA, Billerbeck E, Bukh J, Scheel TKH, Rice CM, Sheahan TP. Brown AJ, et al. Among authors: catanzaro n. Hepatology. 2024 Jan 1;79(1):183-197. doi: 10.1097/HEP.0000000000000547. Epub 2023 Aug 7. Hepatology. 2024. PMID: 37540195 Free PMC article.
Host range, transmissibility and antigenicity of a pangolin coronavirus.
Hou YJ, Chiba S, Leist SR, Meganck RM, Martinez DR, Schäfer A, Catanzaro NJ, Sontake V, West A, Edwards CE, Yount B, Lee RE, Gallant SC, Zost SJ, Powers J, Adams L, Kong EF, Mattocks M, Tata A, Randell SH, Tata PR, Halfmann P, Crowe JE Jr, Kawaoka Y, Baric RS. Hou YJ, et al. Among authors: catanzaro nj. Nat Microbiol. 2023 Oct;8(10):1820-1833. doi: 10.1038/s41564-023-01476-x. Epub 2023 Sep 25. Nat Microbiol. 2023. PMID: 37749254 Free PMC article.
Vaccine-mediated protection against Merbecovirus and Sarbecovirus challenge in mice.
Martinez DR, Schäfer A, Gavitt TD, Mallory ML, Lee E, Catanzaro NJ, Chen H, Gully K, Scobey T, Korategere P, Brown A, Smith L, Parks R, Barr M, Newman A, Bowman C, Powers JM, Soderblom EJ, Mansouri K, Edwards RJ, Baric RS, Haynes BF, Saunders KO. Martinez DR, et al. Among authors: catanzaro nj. Cell Rep. 2023 Oct 31;42(10):113248. doi: 10.1016/j.celrep.2023.113248. Epub 2023 Oct 18. Cell Rep. 2023. PMID: 37858337 Free PMC article.
Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Kapingidza AB, Marston DJ, Harris C, Wrapp D, Winters K, Mielke D, Xiaozhi L, Yin Q, Foulger A, Parks R, Barr M, Newman A, Schäfer A, Eaton A, Flores JM, Harner A, Catanzaro NJ Jr, Mallory ML, Mattocks MD, Beverly C, Rhodes B, Mansouri K, Van Itallie E, Vure P, Dunn B, Keyes T, Stanfield-Oakley S, Woods CW, Petzold EA, Walter EB, Wiehe K, Edwards RJ, Montefiori DC, Ferrari G, Baric R, Cain DW, Saunders KO, Haynes BF, Azoitei ML. Kapingidza AB, et al. Among authors: catanzaro nj jr. Nat Commun. 2023 Nov 30;14(1):7897. doi: 10.1038/s41467-023-43638-9. Nat Commun. 2023. PMID: 38036525 Free PMC article.
29 results