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Page 1
Markers of cell death predict therapy response in patients with cirrhosis and hepatorenal syndrome.
Heinrich S, Austgen T, Castven D, Hess M, Labenz C, Kirstein M, Zimpel C, Stockhoff L, Maasoumy B, Heinrich B, Wedemeyer HH, Galle PR, Binder H, Nguyen-Tat M, Marquardt JU. Heinrich S, et al. Among authors: castven d. United European Gastroenterol J. 2023 Feb;11(1):92-102. doi: 10.1002/ueg2.12337. Epub 2022 Nov 28. United European Gastroenterol J. 2023. PMID: 36441143 Free PMC article.
Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer.
Marquardt JU, Gomez-Quiroz L, Arreguin Camacho LO, Pinna F, Lee YH, Kitade M, Domínguez MP, Castven D, Breuhahn K, Conner EA, Galle PR, Andersen JB, Factor VM, Thorgeirsson SS. Marquardt JU, et al. Among authors: castven d. J Hepatol. 2015 Sep;63(3):661-9. doi: 10.1016/j.jhep.2015.04.018. Epub 2015 May 1. J Hepatol. 2015. PMID: 25937435 Free PMC article.
Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas.
Castven D, Fischer M, Becker D, Heinrich S, Andersen JB, Strand D, Sprinzl MF, Strand S, Czauderna C, Heilmann-Heimbach S, Roessler S, Weinmann A, Wörns MA, Thorgeirsson SS, Galle PR, Matter MS, Lang H, Marquardt JU. Castven D, et al. Oncotarget. 2017 Jul 25;8(30):48688-48700. doi: 10.18632/oncotarget.16231. Oncotarget. 2017. PMID: 28415775 Free PMC article.
Application of patient-derived liver cancer cells for phenotypic characterization and therapeutic target identification.
Castven D, Becker D, Czauderna C, Wilhelm D, Andersen JB, Strand S, Hartmann M, Heilmann-Heimbach S, Roth W, Hartmann N, Straub BK, Mahn FL, Franck S, Pereira S, Haupts A, Vogel A, Wörns MA, Weinmann A, Heinrich S, Lang H, Thorgeirsson SS, Galle PR, Marquardt JU. Castven D, et al. Int J Cancer. 2019 Jun 1;144(11):2782-2794. doi: 10.1002/ijc.32026. Epub 2018 Dec 14. Int J Cancer. 2019. PMID: 30485423 Free article.
Ginkgo biloba induces different gene expression signatures and oncogenic pathways in malignant and non-malignant cells of the liver.
Czauderna C, Palestino-Dominguez M, Castven D, Becker D, Zanon-Rodriguez L, Hajduk J, Mahn FL, Herr M, Strand D, Strand S, Heilmann-Heimbach S, Gomez-Quiroz LE, Wörns MA, Galle PR, Marquardt JU. Czauderna C, et al. Among authors: castven d. PLoS One. 2018 Dec 21;13(12):e0209067. doi: 10.1371/journal.pone.0209067. eCollection 2018. PLoS One. 2018. PMID: 30576355 Free PMC article.
Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis.
Czauderna C, Poplawski A, O'Rourke CJ, Castven D, Pérez-Aguilar B, Becker D, Heilmann-Heimbach S, Odenthal M, Amer W, Schmiel M, Drebber U, Binder H, Ridder DA, Schindeldecker M, Straub BK, Galle PR, Andersen JB, Thorgeirsson SS, Park YN, Marquardt JU. Czauderna C, et al. Among authors: castven d. JCI Insight. 2021 Sep 8;6(17):e146196. doi: 10.1172/jci.insight.146196. JCI Insight. 2021. PMID: 34375307 Free PMC article.
Acquired Resistance to Antiangiogenic Therapies in Hepatocellular Carcinoma Is Mediated by Yes-Associated Protein 1 Activation and Transient Expansion of Stem-Like Cancer Cells.
Castven D, Czauderna C, Becker D, Pereira S, Schmitt J, Weinmann A, Shah V, Hajduk J, Keggenhoff F, Binder H, Keck T, Heilmann-Heimbach S, Wörns MA, Thorgeirsson SS, Breuhahn K, Galle PR, Marquardt JU. Castven D, et al. Hepatol Commun. 2022 May;6(5):1140-1156. doi: 10.1002/hep4.1869. Epub 2021 Nov 24. Hepatol Commun. 2022. PMID: 34817932 Free PMC article.
Severe metabolic alterations in liver cancer lead to ERK pathway activation and drug resistance.
Nwosu ZC, Piorońska W, Battello N, Zimmer AD, Dewidar B, Han M, Pereira S, Blagojevic B, Castven D, Charlestin V, Holenya P, Lochead J, De La Torre C, Gretz N, Sajjakulnukit P, Zhang L, Ward MH, Marquardt JU, di Magliano MP, Lyssiotis CA, Sleeman J, Wölfl S, Ebert MP, Meyer C, Hofmann U, Dooley S. Nwosu ZC, et al. Among authors: castven d. EBioMedicine. 2020 Apr;54:102699. doi: 10.1016/j.ebiom.2020.102699. Epub 2020 Apr 21. EBioMedicine. 2020. PMID: 32330875 Free PMC article.
21 results