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2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice.
Johansson L, Fotsch C, Bartberger MD, Castro VM, Chen M, Emery M, Gustafsson S, Hale C, Hickman D, Homan E, Jordan SR, Komorowski R, Li A, McRae K, Moniz G, Matsumoto G, Orihuela C, Palm G, Veniant M, Wang M, Williams M, Zhang J. Johansson L, et al. Among authors: castro vm. J Med Chem. 2008 May 22;51(10):2933-43. doi: 10.1021/jm701551j. Epub 2008 Apr 18. J Med Chem. 2008. PMID: 18419108
Piperidine amides as 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.
Flyrén K, Bergquist LO, Castro VM, Fotsch C, Johansson L, St Jean DJ Jr, Sutin L, Williams M. Flyrén K, et al. Among authors: castro vm. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3421-5. doi: 10.1016/j.bmcl.2007.03.083. Epub 2007 Mar 30. Bioorg Med Chem Lett. 2007. PMID: 17442567
Oxazolones as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.
Sutin L, Andersson S, Bergquist L, Castro VM, Danielsson E, James S, Henriksson M, Johansson L, Kaiser C, Flyrén K, Williams M. Sutin L, et al. Among authors: castro vm. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4837-40. doi: 10.1016/j.bmcl.2007.06.054. Epub 2007 Jun 20. Bioorg Med Chem Lett. 2007. PMID: 17600707
Validation of electronic health record phenotyping of bipolar disorder cases and controls.
Castro VM, Minnier J, Murphy SN, Kohane I, Churchill SE, Gainer V, Cai T, Hoffnagle AG, Dai Y, Block S, Weill SR, Nadal-Vicens M, Pollastri AR, Rosenquist JN, Goryachev S, Ongur D, Sklar P, Perlis RH, Smoller JW; International Cohort Collection for Bipolar Disorder Consortium. Castro VM, et al. Am J Psychiatry. 2015 Apr;172(4):363-72. doi: 10.1176/appi.ajp.2014.14030423. Epub 2014 Dec 12. Am J Psychiatry. 2015. PMID: 25827034 Free PMC article.
Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder.
Song J, Bergen SE, Di Florio A, Karlsson R, Charney A, Ruderfer DM, Stahl EA; Members of the International Cohort Collection for Bipolar Disorder (ICCBD); Chambert KD, Moran JL, Gordon-Smith K, Forty L, Green EK, Jones I, Jones L, Scolnick EM, Sklar P, Smoller JW, Lichtenstein P, Hultman C, Craddock N, Landén M, Smoller JW, Perlis RH, Lee PH, Castro VM, Hoffnagle AG, Sklar P, Stahl EA, Purcell SM, Ruderfer DM, Charney AW, Roussos P, Michele Pato CP, Medeiros H, Sobel J, Craddock N, Jones I, Forty L, Florio AD, Green E, Jones L, Gordon-Smith K, Landen M, Hultman C, Jureus A, Bergen S, McCarroll S, Moran J, Smoller JW, Chambert K, Belliveau RA. Song J, et al. Among authors: castro vm. Mol Psychiatry. 2016 Sep;21(9):1290-7. doi: 10.1038/mp.2015.165. Epub 2015 Oct 27. Mol Psychiatry. 2016. PMID: 26503763 Free PMC article.
Predicting Suicidal Behavior From Longitudinal Electronic Health Records.
Barak-Corren Y, Castro VM, Javitt S, Hoffnagle AG, Dai Y, Perlis RH, Nock MK, Smoller JW, Reis BY. Barak-Corren Y, et al. Among authors: castro vm. Am J Psychiatry. 2017 Feb 1;174(2):154-162. doi: 10.1176/appi.ajp.2016.16010077. Epub 2016 Sep 9. Am J Psychiatry. 2017. PMID: 27609239
130 results