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Genomic and evolutionary classification of lung cancer in never smokers.
Zhang T, Joubert P, Ansari-Pour N, Zhao W, Hoang PH, Lokanga R, Moye AL, Rosenbaum J, Gonzalez-Perez A, Martínez-Jiménez F, Castro A, Muscarella LA, Hofman P, Consonni D, Pesatori AC, Kebede M, Li M, Gould Rothberg BE, Peneva I, Schabath MB, Poeta ML, Costantini M, Hirsch D, Heselmeyer-Haddad K, Hutchinson A, Olanich M, Lawrence SM, Lenz P, Duggan M, Bhawsar PMS, Sang J, Kim J, Mendoza L, Saini N, Klimczak LJ, Islam SMA, Otlu B, Khandekar A, Cole N, Stewart DR, Choi J, Brown KM, Caporaso NE, Wilson SH, Pommier Y, Lan Q, Rothman N, Almeida JS, Carter H, Ried T, Kim CF, Lopez-Bigas N, Garcia-Closas M, Shi J, Bossé Y, Zhu B, Gordenin DA, Alexandrov LB, Chanock SJ, Wedge DC, Landi MT. Zhang T, et al. Among authors: castro a. Nat Genet. 2021 Sep;53(9):1348-1359. doi: 10.1038/s41588-021-00920-0. Epub 2021 Sep 6. Nat Genet. 2021. PMID: 34493867 Free PMC article.
MHC-I genotype and tumor mutational burden predict response to immunotherapy.
Goodman AM, Castro A, Pyke RM, Okamura R, Kato S, Riviere P, Frampton G, Sokol E, Zhang X, Ball ED, Carter H, Kurzrock R. Goodman AM, et al. Among authors: castro a. Genome Med. 2020 May 19;12(1):45. doi: 10.1186/s13073-020-00743-4. Genome Med. 2020. PMID: 32430031 Free PMC article.
Telomerase and CD4 T Cell Immunity in Cancer.
Dosset M, Castro A, Carter H, Zanetti M. Dosset M, et al. Among authors: castro a. Cancers (Basel). 2020 Jun 25;12(6):1687. doi: 10.3390/cancers12061687. Cancers (Basel). 2020. PMID: 32630460 Free PMC article. Review.
Strength of immune selection in tumors varies with sex and age.
Castro A, Pyke RM, Zhang X, Thompson WK, Day CP, Alexandrov LB, Zanetti M, Carter H. Castro A, et al. Nat Commun. 2020 Aug 17;11(1):4128. doi: 10.1038/s41467-020-17981-0. Nat Commun. 2020. PMID: 32807809 Free PMC article.
Neoantigen Controversies.
Castro A, Zanetti M, Carter H. Castro A, et al. Annu Rev Biomed Data Sci. 2021 Jul 20;4:227-253. doi: 10.1146/annurev-biodatasci-092820-112713. Epub 2021 May 11. Annu Rev Biomed Data Sci. 2021. PMID: 34465181 Free PMC article. Review.
4,591 results