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Recombinant PrPSc shares structural features with brain-derived PrPSc: Insights from limited proteolysis.
Sevillano AM, Fernández-Borges N, Younas N, Wang F, R Elezgarai S, Bravo S, Vázquez-Fernández E, Rosa I, Eraña H, Gil D, Veiga S, Vidal E, Erickson-Beltran ML, Guitián E, Silva CJ, Nonno R, Ma J, Castilla J, R Requena J. Sevillano AM, et al. Among authors: castilla j. PLoS Pathog. 2018 Jan 31;14(1):e1006797. doi: 10.1371/journal.ppat.1006797. eCollection 2018 Jan. PLoS Pathog. 2018. PMID: 29385212 Free PMC article.
In vitro studies of the transmission barrier.
Fernández-Borges N, de Castro J, Castilla J. Fernández-Borges N, et al. Among authors: castilla j. Prion. 2009 Oct-Dec;3(4):220-3. doi: 10.4161/pri.3.4.10500. Epub 2009 Oct 30. Prion. 2009. PMID: 20009509 Free PMC article. Review.
A molecular switch controls interspecies prion disease transmission in mice.
Sigurdson CJ, Nilsson KP, Hornemann S, Manco G, Fernández-Borges N, Schwarz P, Castilla J, Wüthrich K, Aguzzi A. Sigurdson CJ, et al. Among authors: castilla j. J Clin Invest. 2010 Jul;120(7):2590-9. doi: 10.1172/JCI42051. Epub 2010 Jun 14. J Clin Invest. 2010. PMID: 20551516 Free PMC article.
Rabbits are not resistant to prion infection.
Chianini F, Fernández-Borges N, Vidal E, Gibbard L, Pintado B, de Castro J, Priola SA, Hamilton S, Eaton SL, Finlayson J, Pang Y, Steele P, Reid HW, Dagleish MP, Castilla J. Chianini F, et al. Among authors: castilla j. Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):5080-5. doi: 10.1073/pnas.1120076109. Epub 2012 Mar 13. Proc Natl Acad Sci U S A. 2012. PMID: 22416127 Free PMC article.
Structure of the β2-α2 loop and interspecies prion transmission.
Bett C, Fernández-Borges N, Kurt TD, Lucero M, Nilsson KP, Castilla J, Sigurdson CJ. Bett C, et al. Among authors: castilla j. FASEB J. 2012 Jul;26(7):2868-76. doi: 10.1096/fj.11-200923. Epub 2012 Apr 9. FASEB J. 2012. PMID: 22490928 Free PMC article.
Naturally prion resistant mammals: a utopia?
Fernández-Borges N, Chianini F, Eraña H, Vidal E, Eaton SL, Pintado B, Finlayson J, Dagleish MP, Castilla J. Fernández-Borges N, et al. Among authors: castilla j. Prion. 2012 Nov-Dec;6(5):425-9. doi: 10.4161/pri.22057. Epub 2012 Sep 6. Prion. 2012. PMID: 22954650 Free PMC article.
688 results