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Homozygous ALS-linked mutations in TARDBP/TDP-43 lead to hypoactivity and synaptic abnormalities in human iPSC-derived motor neurons.
iScience. 2024 Feb 9;27(3):109166. doi: 10.1016/j.isci.2024.109166. eCollection 2024 Mar 15.
iScience. 2024.
PMID: 38433895
Free PMC article.
USP19 deubiquitinase inactivation regulates α-synuclein ubiquitination and inhibits accumulation of Lewy body-like aggregates in mice.
Schorova L, Bedard N, Khayachi A, Ho HH, Bolivar-Pedroso J, Huynh J, Piccirelli M, Wang Y, Plourde M, Luo W, Del Cid-Pellitero E, Shlaifer I, Castellanos-Montiel MJ, Yu Z, Valenzuela DVC, Lacalle-Aurioles M, Kriz A, Ye Y, Durcan TM, Wing SS.
Schorova L, et al. Among authors: castellanos montiel mj.
NPJ Parkinsons Dis. 2023 Nov 28;9(1):157. doi: 10.1038/s41531-023-00601-1.
NPJ Parkinsons Dis. 2023.
PMID: 38017009
Free PMC article.
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An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids.
Castellanos-Montiel MJ, Chaineau M, Franco-Flores AK, Haghi G, Carrillo-Valenzuela D, Reintsch WE, Chen CX, Durcan TM.
Castellanos-Montiel MJ, et al.
Cells. 2023 Feb 8;12(4):545. doi: 10.3390/cells12040545.
Cells. 2023.
PMID: 36831212
Free PMC article.
Item in Clipboard
TDP-43 dysregulation and neuromuscular junction disruption in amyotrophic lateral sclerosis.
Lépine S, Castellanos-Montiel MJ, Durcan TM.
Lépine S, et al. Among authors: castellanos montiel mj.
Transl Neurodegener. 2022 Dec 27;11(1):56. doi: 10.1186/s40035-022-00331-z.
Transl Neurodegener. 2022.
PMID: 36575535
Free PMC article.
Review.
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A streamlined CRISPR workflow to introduce mutations and generate isogenic iPSCs for modeling amyotrophic lateral sclerosis.
Deneault E, Chaineau M, Nicouleau M, Castellanos Montiel MJ, Franco Flores AK, Haghi G, Chen CX, Abdian N, Shlaifer I, Beitel LK, Durcan TM.
Deneault E, et al. Among authors: castellanos montiel mj.
Methods. 2022 Jul;203:297-310. doi: 10.1016/j.ymeth.2021.09.002. Epub 2021 Sep 6.
Methods. 2022.
PMID: 34500068
Free article.
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The Neglected Genes of ALS: Cytoskeletal Dynamics Impact Synaptic Degeneration in ALS.
Castellanos-Montiel MJ, Chaineau M, Durcan TM.
Castellanos-Montiel MJ, et al.
Front Cell Neurosci. 2020 Nov 13;14:594975. doi: 10.3389/fncel.2020.594975. eCollection 2020.
Front Cell Neurosci. 2020.
PMID: 33281562
Free PMC article.
Review.
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Modeling the neuromuscular junction in vitro: an approach to study neuromuscular junction disorders.
Castellanos-Montiel MJ, Velasco I, Escobedo-Avila I.
Castellanos-Montiel MJ, et al.
Ann N Y Acad Sci. 2021 Mar;1488(1):3-15. doi: 10.1111/nyas.14504. Epub 2020 Oct 10.
Ann N Y Acad Sci. 2021.
PMID: 33040338
Review.
Item in Clipboard
The Non-Survival Effects of Glial Cell Line-Derived Neurotrophic Factor on Neural Cells.
Cortés D, Carballo-Molina OA, Castellanos-Montiel MJ, Velasco I.
Cortés D, et al. Among authors: castellanos montiel mj.
Front Mol Neurosci. 2017 Aug 22;10:258. doi: 10.3389/fnmol.2017.00258. eCollection 2017.
Front Mol Neurosci. 2017.
PMID: 28878618
Free PMC article.
Review.
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