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Central anorexigenic actions of bile acids are mediated by TGR5.
Perino A, Velázquez-Villegas LA, Bresciani N, Sun Y, Huang Q, Fénelon VS, Castellanos-Jankiewicz A, Zizzari P, Bruschetta G, Jin S, Baleisyte A, Gioiello A, Pellicciari R, Ivanisevic J, Schneider BL, Diano S, Cota D, Schoonjans K. Perino A, et al. Among authors: castellanos jankiewicz a. Nat Metab. 2021 May;3(5):595-603. doi: 10.1038/s42255-021-00398-4. Epub 2021 May 24. Nat Metab. 2021. PMID: 34031591 Free PMC article.
Hypothalamic bile acid-TGR5 signaling protects from obesity.
Castellanos-Jankiewicz A, Guzmán-Quevedo O, Fénelon VS, Zizzari P, Quarta C, Bellocchio L, Tailleux A, Charton J, Fernandois D, Henricsson M, Piveteau C, Simon V, Allard C, Quemener S, Guinot V, Hennuyer N, Perino A, Duveau A, Maitre M, Leste-Lasserre T, Clark S, Dupuy N, Cannich A, Gonzales D, Deprez B, Mithieux G, Dombrowicz D, Bäckhed F, Prevot V, Marsicano G, Staels B, Schoonjans K, Cota D. Castellanos-Jankiewicz A, et al. Cell Metab. 2021 Jul 6;33(7):1483-1492.e10. doi: 10.1016/j.cmet.2021.04.009. Epub 2021 Apr 21. Cell Metab. 2021. PMID: 33887197 Free article.
A genetic variant of the CAPN10 gene in Mexican subjects with dyslipidemia is associated with increased HDL-cholesterol concentrations after the consumption of a soy protein and soluble fiber dietary portfolio.
Guevara-Cruz M, Torres N, Tovar AR, Tejero ME, Castellanos-Jankiewicz A, del Bosque-Plata L. Guevara-Cruz M, et al. Among authors: castellanos jankiewicz a. Nutr Hosp. 2014 Sep 1;30(3):671-7. doi: 10.3305/nh.2014.30.3.7611. Nutr Hosp. 2014. PMID: 25238846 Free article.