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Page 1
Hydrogen sulfide donor AP123 restores endothelial nitric oxide-dependent vascular function in hyperglycemia via a CREB-dependent pathway.
Montanaro R, Vellecco V, Torregrossa R, Casillo GM, Manzo OL, Mitidieri E, Bucci M, Castaldo S, Sorrentino R, Whiteman M, Smimmo M, Carriero F, Terrazzano G, Cirino G, d'Emmanuele di Villa Bianca R, Brancaleone V. Montanaro R, et al. Among authors: casillo gm. Redox Biol. 2023 Jun;62:102657. doi: 10.1016/j.redox.2023.102657. Epub 2023 Mar 4. Redox Biol. 2023. PMID: 36913800 Free PMC article.
IL-17-induced inflammation modulates the mPGES-1/PPAR-γ pathway in monocytes/macrophages.
Raucci F, Saviano A, Casillo GM, Guerra-Rodriguez M, Mansour AA, Piccolo M, Ferraro MG, Panza E, Vellecco V, Irace C, Caso F, Scarpa R, Mascolo N, Alfaifi M, Iqbal AJ, Maione F. Raucci F, et al. Among authors: casillo gm. Br J Pharmacol. 2022 May;179(9):1857-1873. doi: 10.1111/bph.15413. Epub 2021 Mar 21. Br J Pharmacol. 2022. PMID: 33595097 Free article.
Interleukin-17A (IL-17A): A silent amplifier of COVID-19.
Maione F, Casillo GM, Raucci F, Salvatore C, Ambrosini G, Costa L, Scarpa R, Caso F, Bucci M. Maione F, et al. Among authors: casillo gm. Biomed Pharmacother. 2021 Oct;142:111980. doi: 10.1016/j.biopha.2021.111980. Epub 2021 Jul 29. Biomed Pharmacother. 2021. PMID: 34364043 Free PMC article.
Phosphodiesterases S-sulfhydration contributes to human skeletal muscle function.
Vellecco V, Panza E, Bibli SI, Casillo GM, Raucci F, Manzo OL, Smimmo M, Villani R, Cavezza MR, Fleming I, d'Emmanuele di Villa Bianca R, Maione F, Cirino G, Bucci M. Vellecco V, et al. Among authors: casillo gm. Pharmacol Res. 2022 Mar;177:106108. doi: 10.1016/j.phrs.2022.106108. Epub 2022 Feb 1. Pharmacol Res. 2022. PMID: 35121122
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio.
Saviano A, Raucci F, Casillo GM, Mansour AA, Piccolo V, Montesano C, Smimmo M, Vellecco V, Capasso G, Boscaino A, Summa V, Mascolo N, Iqbal AJ, Sorrentino R, d'Emmanuele di Villa Bianca R, Bucci M, Brancaleone V, Maione F. Saviano A, et al. Among authors: casillo gm. Pharmacol Res. 2022 Aug;182:106283. doi: 10.1016/j.phrs.2022.106283. Epub 2022 Jun 1. Pharmacol Res. 2022. PMID: 35662629
Interleukin-17 (IL-17) triggers systemic inflammation, peripheral vascular dysfunction, and related prothrombotic state in a mouse model of Alzheimer's disease.
Vellecco V, Saviano A, Raucci F, Casillo GM, Mansour AA, Panza E, Mitidieri E, Femminella GD, Ferrara N, Cirino G, Sorrentino R, Iqbal AJ, d'Emmanuele di Villa Bianca R, Bucci M, Maione F. Vellecco V, et al. Among authors: casillo gm. Pharmacol Res. 2023 Jan;187:106595. doi: 10.1016/j.phrs.2022.106595. Epub 2022 Dec 5. Pharmacol Res. 2023. PMID: 36470548 Free article.
New biologic (Ab-IPL-IL-17) for IL-17-mediated diseases: identification of the bioactive sequence (nIL-17) for IL-17A/F function.
Saviano A, Manosour AA, Raucci F, Merlino F, Marigliano N, Schettino A, Wahid M, Begum J, Filer A, Manning JE, Casillo GM, Piccolo M, Ferraro MG, Marzano S, Russomanno P, Bellavita R, Irace C, Amato J, Alfaifi M, Rimmer P, Iqbal T, Pieretti S, Vellecco V, Caso F, Costa L, Giacomelli R, Scarpa R, Cirino G, Bucci M, McGettrick HM, Grieco P, Iqbal AJ, Maione F. Saviano A, et al. Among authors: casillo gm. Ann Rheum Dis. 2023 Nov;82(11):1415-1428. doi: 10.1136/ard-2023-224479. Epub 2023 Aug 14. Ann Rheum Dis. 2023. PMID: 37580108 Free PMC article.
Hydrogen sulfide dysfunction in metabolic syndrome-associated vascular complications involves cGMP regulation through soluble guanylyl cyclase persulfidation.
Smimmo M, Casale V, Casillo GM, Mitidieri E, d'Emmanuele di Villa Bianca R, Bello I, Schettino A, Montanaro R, Brancaleone V, Indolfi C, Cirino G, Di Lorenzo A, Bucci M, Panza E, Vellecco V. Smimmo M, et al. Among authors: casillo gm. Biomed Pharmacother. 2024 May;174:116466. doi: 10.1016/j.biopha.2024.116466. Epub 2024 Mar 28. Biomed Pharmacother. 2024. PMID: 38552439 Free article.
Present Status and Future Trends of Natural-Derived Compounds Targeting T Helper (Th) 17 and Microsomal Prostaglandin E Synthase-1 (mPGES-1) as Alternative Therapies for Autoimmune and Inflammatory-Based Diseases.
Saviano A, Raucci F, Casillo GM, Indolfi C, Pernice A, Foreste C, Iqbal AJ, Mascolo N, Maione F. Saviano A, et al. Among authors: casillo gm. Molecules. 2020 Dec 18;25(24):6016. doi: 10.3390/molecules25246016. Molecules. 2020. PMID: 33353211 Free PMC article. Review.
16 results