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High-density lipoproteins suppress Aβ-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture.
Robert J, Button EB, Stukas S, Boyce GK, Gibbs E, Cowan CM, Gilmour M, Cheng WH, Soo SK, Yuen B, Bahrabadi A, Kang K, Kulic I, Francis G, Cashman N, Wellington CL. Robert J, et al. Among authors: cashman n. Mol Neurodegener. 2017 Aug 22;12(1):60. doi: 10.1186/s13024-017-0201-0. Mol Neurodegener. 2017. PMID: 28830501 Free PMC article.
Intermolecular transmission of superoxide dismutase 1 misfolding in living cells.
Grad LI, Guest WC, Yanai A, Pokrishevsky E, O'Neill MA, Gibbs E, Semenchenko V, Yousefi M, Wishart DS, Plotkin SS, Cashman NR. Grad LI, et al. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16398-403. doi: 10.1073/pnas.1102645108. Epub 2011 Sep 19. Proc Natl Acad Sci U S A. 2011. PMID: 21930926 Free PMC article.
A Rational Structured Epitope Defines a Distinct Subclass of Toxic Amyloid-beta Oligomers.
Silverman JM, Gibbs E, Peng X, Martens KM, Balducci C, Wang J, Yousefi M, Cowan CM, Lamour G, Louadi S, Ban Y, Robert J, Stukas S, Forloni G, Hsiung GR, Plotkin SS, Wellington CL, Cashman NR. Silverman JM, et al. ACS Chem Neurosci. 2018 Jul 18;9(7):1591-1606. doi: 10.1021/acschemneuro.7b00469. Epub 2018 Apr 16. ACS Chem Neurosci. 2018. PMID: 29614860
CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1.
Silverman JM, Christy D, Shyu CC, Moon KM, Fernando S, Gidden Z, Cowan CM, Ban Y, Stacey RG, Grad LI, McAlary L, Mackenzie IR, Foster LJ, Cashman NR. Silverman JM, et al. J Biol Chem. 2019 Mar 8;294(10):3744-3759. doi: 10.1074/jbc.RA118.004825. Epub 2019 Jan 11. J Biol Chem. 2019. PMID: 30635404 Free PMC article.
235 results