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Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM- Lung Cancer-Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis.
Bertolini G, D'Amico L, Moro M, Landoni E, Perego P, Miceli R, Gatti L, Andriani F, Wong D, Caserini R, Tortoreto M, Milione M, Ferracini R, Mariani L, Pastorino U, Roato I, Sozzi G, Roz L. Bertolini G, et al. Among authors: caserini r. Cancer Res. 2015 Sep 1;75(17):3636-49. doi: 10.1158/0008-5472.CAN-14-3781. Epub 2015 Jul 3. Cancer Res. 2015. PMID: 26141860
Synergistic Activation upon MET and ALK Coamplification Sustains Targeted Therapy in Sarcomatoid Carcinoma, a Deadly Subtype of Lung Cancer.
Pelosi G, Gasparini P, Conte D, Fabbri A, Perrone F, Tamborini E, Pupa SM, Ciravolo V, Caserini R, Rossi G, Cavazza A, Papotti M, Nakatani Y, Maisonneuve P, Pastorino U, Sozzi G. Pelosi G, et al. Among authors: caserini r. J Thorac Oncol. 2016 May;11(5):718-728. doi: 10.1016/j.jtho.2016.01.009. Epub 2016 Jan 22. J Thorac Oncol. 2016. PMID: 26804638 Free article.
Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment.
Bertolini G, Roz L, Perego P, Tortoreto M, Fontanella E, Gatti L, Pratesi G, Fabbri A, Andriani F, Tinelli S, Roz E, Caserini R, Lo Vullo S, Camerini T, Mariani L, Delia D, Calabrò E, Pastorino U, Sozzi G. Bertolini G, et al. Among authors: caserini r. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16281-6. doi: 10.1073/pnas.0905653106. Epub 2009 Sep 10. Proc Natl Acad Sci U S A. 2009. PMID: 19805294 Free PMC article.
Conversion to stem-cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells.
Andriani F, Bertolini G, Facchinetti F, Baldoli E, Moro M, Casalini P, Caserini R, Milione M, Leone G, Pelosi G, Pastorino U, Sozzi G, Roz L. Andriani F, et al. Among authors: caserini r. Mol Oncol. 2016 Feb;10(2):253-71. doi: 10.1016/j.molonc.2015.10.002. Epub 2015 Oct 22. Mol Oncol. 2016. PMID: 26514616 Free PMC article.
Anaplastic lymphoma kinase aberrations correlate with metastatic features in pediatric rhabdomyosarcoma.
Gasparini P, Casanova M, Villa R, Collini P, Alaggio R, Zin A, Bonvini P, Antonescu CR, Boldrini R, Caserini R, Moro M, Centonze G, Meazza C, Massimino M, Bergamaschi L, Luksch R, Chiaravalli S, Bisogno G, Zaffaroni N, Daidone MG, Sozzi G, Ferrari A. Gasparini P, et al. Among authors: caserini r. Oncotarget. 2016 Sep 13;7(37):58903-58914. doi: 10.18632/oncotarget.10368. Oncotarget. 2016. PMID: 27385213 Free PMC article.