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Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms.
Beltra JC, Manne S, Abdel-Hakeem MS, Kurachi M, Giles JR, Chen Z, Casella V, Ngiow SF, Khan O, Huang YJ, Yan P, Nzingha K, Xu W, Amaravadi RK, Xu X, Karakousis GC, Mitchell TC, Schuchter LM, Huang AC, Wherry EJ. Beltra JC, et al. Among authors: casella v. Immunity. 2020 May 19;52(5):825-841.e8. doi: 10.1016/j.immuni.2020.04.014. Epub 2020 May 11. Immunity. 2020. PMID: 32396847 Free PMC article.
XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections.
Domenjo-Vila E, Casella V, Iwabuchi R, Fossum E, Pedragosa M, Castellví Q, Cebollada Rica P, Kaisho T, Terahara K, Bocharov G, Argilaguet J, Meyerhans A. Domenjo-Vila E, et al. Among authors: casella v. Cell Rep. 2023 Feb 28;42(2):112123. doi: 10.1016/j.celrep.2023.112123. Epub 2023 Feb 14. Cell Rep. 2023. PMID: 36795562 Free article.
Systems analysis reveals complex biological processes during virus infection fate decisions.
Argilaguet J, Pedragosa M, Esteve-Codina A, Riera G, Vidal E, Peligero-Cruz C, Casella V, Andreu D, Kaisho T, Bocharov G, Ludewig B, Heath S, Meyerhans A. Argilaguet J, et al. Among authors: casella v. Genome Res. 2019 Jun;29(6):907-919. doi: 10.1101/gr.241372.118. Epub 2019 May 28. Genome Res. 2019. PMID: 31138618 Free PMC article.
Numbers Game and Immune Geography as Determinants of Coronavirus Pathogenicity.
Bocharov G, Casella V, Argilaguet J, Grebennikov D, Güerri-Fernandez R, Ludewig B, Meyerhans A. Bocharov G, et al. Among authors: casella v. Front Cell Infect Microbiol. 2020 Oct 23;10:559209. doi: 10.3389/fcimb.2020.559209. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 33194799 Free PMC article. No abstract available.
Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure.
Beltra JC, Abdel-Hakeem MS, Manne S, Zhang Z, Huang H, Kurachi M, Su L, Picton L, Ngiow SF, Muroyama Y, Casella V, Huang YJ, Giles JR, Mathew D, Belman J, Klapholz M, Decaluwe H, Huang AC, Berger SL, Garcia KC, Wherry EJ. Beltra JC, et al. Among authors: casella v. Immunity. 2023 Dec 12;56(12):2699-2718.e11. doi: 10.1016/j.immuni.2023.11.005. Immunity. 2023. PMID: 38091951
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