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Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure.
Beltra JC, Abdel-Hakeem MS, Manne S, Zhang Z, Huang H, Kurachi M, Su L, Picton L, Ngiow SF, Muroyama Y, Casella V, Huang YJ, Giles JR, Mathew D, Belman J, Klapholz M, Decaluwe H, Huang AC, Berger SL, Garcia KC, Wherry EJ. Beltra JC, et al. Among authors: casella v. Immunity. 2023 Dec 12;56(12):2699-2718.e11. doi: 10.1016/j.immuni.2023.11.005. Immunity. 2023. PMID: 38091951
XCR1+ DCs are critical for T cell-mediated immunotherapy of chronic viral infections.
Domenjo-Vila E, Casella V, Iwabuchi R, Fossum E, Pedragosa M, Castellví Q, Cebollada Rica P, Kaisho T, Terahara K, Bocharov G, Argilaguet J, Meyerhans A. Domenjo-Vila E, et al. Among authors: casella v. Cell Rep. 2023 Feb 28;42(2):112123. doi: 10.1016/j.celrep.2023.112123. Epub 2023 Feb 14. Cell Rep. 2023. PMID: 36795562 Free article.
Impact of Natural Killer (NK) Cells on Immune Reconstitution, and Their Potential as a Biomarker of Disease Activity, in Alemtuzumab-Treated Patients with Relapsing Remitting Multiple Sclerosis: An Observational Study.
Palmeri S, Ponzano M, Ivaldi F, Signori A, Lapucci C, Casella V, Ferrò MT, Vigo T, Inglese M, Mancardi GL, Uccelli A, Laroni A. Palmeri S, et al. Among authors: casella v. CNS Drugs. 2022 Jan;36(1):83-96. doi: 10.1007/s40263-021-00875-0. Epub 2021 Dec 11. CNS Drugs. 2022. PMID: 34894339
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