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CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency.
Smoum R, Baraghithy S, Chourasia M, Breuer A, Mussai N, Attar-Namdar M, Kogan NM, Raphael B, Bolognini D, Cascio MG, Marini P, Pertwee RG, Shurki A, Mechoulam R, Bab I. Smoum R, et al. Among authors: cascio mg. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8774-9. doi: 10.1073/pnas.1503395112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124120 Free PMC article.
Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor.
Laprairie RB, Kulkarni PM, Deschamps JR, Kelly MEM, Janero DR, Cascio MG, Stevenson LA, Pertwee RG, Kenakin TP, Denovan-Wright EM, Thakur GA. Laprairie RB, et al. Among authors: cascio mg. ACS Chem Neurosci. 2017 Jun 21;8(6):1188-1203. doi: 10.1021/acschemneuro.6b00310. Epub 2017 Feb 7. ACS Chem Neurosci. 2017. PMID: 28103441
Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s).
Kulkarni PM, Kulkarni AR, Korde A, Tichkule RB, Laprairie RB, Denovan-Wright EM, Zhou H, Janero DR, Zvonok N, Makriyannis A, Cascio MG, Pertwee RG, Thakur GA. Kulkarni PM, et al. Among authors: cascio mg. J Med Chem. 2016 Jan 14;59(1):44-60. doi: 10.1021/acs.jmedchem.5b01303. Epub 2015 Nov 28. J Med Chem. 2016. PMID: 26529344 Free PMC article.
Novel bioactive metabolites of dipyrone (metamizol).
Rogosch T, Sinning C, Podlewski A, Watzer B, Schlosburg J, Lichtman AH, Cascio MG, Bisogno T, Di Marzo V, Nüsing R, Imming P. Rogosch T, et al. Among authors: cascio mg. Bioorg Med Chem. 2012 Jan 1;20(1):101-7. doi: 10.1016/j.bmc.2011.11.028. Epub 2011 Nov 25. Bioorg Med Chem. 2012. PMID: 22172309 Free PMC article.
73 results