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α-Synuclein in Parkinson's disease: causal or bystander?
Riederer P, Berg D, Casadei N, Cheng F, Classen J, Dresel C, Jost W, Krüger R, Müller T, Reichmann H, Rieß O, Storch A, Strobel S, van Eimeren T, Völker HU, Winkler J, Winklhofer KF, Wüllner U, Zunke F, Monoranu CM. Riederer P, et al. Among authors: casadei n. J Neural Transm (Vienna). 2019 Jul;126(7):815-840. doi: 10.1007/s00702-019-02025-9. Epub 2019 Jun 25. J Neural Transm (Vienna). 2019. PMID: 31240402 Review.
Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice.
Nuber S, Franck T, Wolburg H, Schumann U, Casadei N, Fischer K, Calaminus C, Pichler BJ, Chanarat S, Teismann P, Schulz JB, Luft AR, Tomiuk J, Wilbertz J, Bornemann A, Krüger R, Riess O. Nuber S, et al. Among authors: casadei n. Neurogenetics. 2010 Feb;11(1):107-20. doi: 10.1007/s10048-009-0212-2. Neurogenetics. 2010. PMID: 19760259
A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats.
Nuber S, Harmuth F, Kohl Z, Adame A, Trejo M, Schönig K, Zimmermann F, Bauer C, Casadei N, Giel C, Calaminus C, Pichler BJ, Jensen PH, Müller CP, Amato D, Kornhuber J, Teismann P, Yamakado H, Takahashi R, Winkler J, Masliah E, Riess O. Nuber S, et al. Among authors: casadei n. Brain. 2013 Feb;136(Pt 2):412-32. doi: 10.1093/brain/aws358. Brain. 2013. PMID: 23413261 Free PMC article.
Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice.
Casadei N, Pöhler AM, Tomás-Zapico C, Torres-Peraza J, Schwedhelm I, Witz A, Zamolo I, De Heer R, Spruijt B, Noldus LP, Klucken J, Lucas JJ, Kahle PJ, Krüger R, Riess O, Nuber S. Casadei N, et al. Hum Mol Genet. 2014 Feb 1;23(3):767-81. doi: 10.1093/hmg/ddt467. Epub 2013 Sep 24. Hum Mol Genet. 2014. PMID: 24064336
Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.
Diepenbroek M, Casadei N, Esmer H, Saido TC, Takano J, Kahle PJ, Nixon RA, Rao MV, Melki R, Pieri L, Helling S, Marcus K, Krueger R, Masliah E, Riess O, Nuber S. Diepenbroek M, et al. Among authors: casadei n. Hum Mol Genet. 2014 Aug 1;23(15):3975-89. doi: 10.1093/hmg/ddu112. Epub 2014 Mar 11. Hum Mol Genet. 2014. PMID: 24619358 Free PMC article.
Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors.
Van der Perren A, Toelen J, Casteels C, Macchi F, Van Rompuy AS, Sarre S, Casadei N, Nuber S, Himmelreich U, Osorio Garcia MI, Michotte Y, D'Hooge R, Bormans G, Van Laere K, Gijsbers R, Van den Haute C, Debyser Z, Baekelandt V. Van der Perren A, et al. Among authors: casadei n. Neurobiol Aging. 2015 Mar;36(3):1543-58. doi: 10.1016/j.neurobiolaging.2014.11.015. Epub 2014 Dec 17. Neurobiol Aging. 2015. PMID: 25599874
83 results