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A selective p53 activator and anticancer agent to improve colorectal cancer therapy.
Ramos H, Soares MIL, Silva J, Raimundo L, Calheiros J, Gomes C, Reis F, Monteiro FA, Nunes C, Reis S, Bosco B, Piazza S, Domingues L, Chlapek P, Vlcek P, Fabian P, Rajado AT, Carvalho ATP, Veselska R, Inga A, Pinho E Melo TMVD, Saraiva L. Ramos H, et al. Among authors: carvalho atp. Cell Rep. 2021 Apr 13;35(2):108982. doi: 10.1016/j.celrep.2021.108982. Cell Rep. 2021. PMID: 33852837 Free article.
SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations.
Gomes AS, Ramos H, Gomes S, Loureiro JB, Soares J, Barcherini V, Monti P, Fronza G, Oliveira C, Domingues L, Bastos M, Dourado DFAR, Carvalho AL, Romão MJ, Pinheiro B, Marcelo F, Carvalho A, Santos MMM, Saraiva L. Gomes AS, et al. Biochim Biophys Acta Gen Subj. 2020 Jan;1864(1):129440. doi: 10.1016/j.bbagen.2019.129440. Epub 2019 Sep 16. Biochim Biophys Acta Gen Subj. 2020. PMID: 31536751
In vitro mechanistic studies on α-amanitin and its putative antidotes.
Rodrigues DF, Pires das Neves R, Carvalho ATP, Lourdes Bastos M, Costa VM, Carvalho F. Rodrigues DF, et al. Among authors: carvalho atp, carvalho f. Arch Toxicol. 2020 Jun;94(6):2061-2078. doi: 10.1007/s00204-020-02718-1. Epub 2020 Mar 19. Arch Toxicol. 2020. PMID: 32193566
56 results