Caruso A - Search Results

1

Understanding the Half-Life Extension of Intravitreally Administered Antibodies Binding to Ocular Albumin.

Hauri S, Jakubiak P, Fueth M, Dengl S, Belli S, Alvarez-Sánchez R, Caruso A. Hauri S, et al. Among authors: caruso a. Pharmaceutics. 2020 Aug 26;12(9):810. doi: 10.3390/pharmaceutics12090810. Pharmaceutics. 2020. PMID: 32858986 Free PMC article.

2

PK/PD assessment in CNS drug discovery: Prediction of CSF concentration in rodents for P-glycoprotein substrates and application to in vivo potency estimation.

Caruso A, Alvarez-Sánchez R, Hillebrecht A, Poirier A, Schuler F, Lavé T, Funk C, Belli S. Caruso A, et al. Biochem Pharmacol. 2013 Jun 1;85(11):1684-99. doi: 10.1016/j.bcp.2013.02.021. Epub 2013 Feb 27. Biochem Pharmacol. 2013. PMID: 23454189

3

Theoretical Insights into the Retinal Dynamics of Vascular Endothelial Growth Factor in Patients Treated with Ranibizumab, Based on an Ocular Pharmacokinetic/Pharmacodynamic Model.

Hutton-Smith LA, Gaffney EA, Byrne HM, Caruso A, Maini PK, Mazer NA. Hutton-Smith LA, et al. Among authors: caruso a. Mol Pharm. 2018 Jul 2;15(7):2770-2784. doi: 10.1021/acs.molpharmaceut.8b00280. Epub 2018 May 29. Mol Pharm. 2018. PMID: 29734810

4

Ocular Half-Life of Intravitreal Biologics in Humans and Other Species: Meta-Analysis and Model-Based Prediction.

Caruso A, Füth M, Alvarez-Sánchez R, Belli S, Diack C, Maass KF, Schwab D, Kettenberger H, Mazer NA. Caruso A, et al. Mol Pharm. 2020 Feb 3;17(2):695-709. doi: 10.1021/acs.molpharmaceut.9b01191. Epub 2020 Jan 16. Mol Pharm. 2020. PMID: 31876425

5

Ocular Pharmacokinetics of Intravitreally Injected Protein Therapeutics: Comparison among Standard-of-Care Formats.

Jakubiak P, Alvarez-Sánchez R, Fueth M, Broders O, Kettenberger H, Stubenrauch K, Caruso A. Jakubiak P, et al. Among authors: caruso a. Mol Pharm. 2021 Jun 7;18(6):2208-2217. doi: 10.1021/acs.molpharmaceut.0c01218. Epub 2021 May 20. Mol Pharm. 2021. PMID: 34014104

6

Are Ocular and Serum Half-Lives After Ranibizumab Intravitreal Injection Dependent on Dose?

van Donge T, Brizzi F, Caruso A, Fueth M, Steiert B. van Donge T, et al. Among authors: caruso a. Transl Vis Sci Technol. 2023 Apr 3;12(4):9. doi: 10.1167/tvst.12.4.9. Transl Vis Sci Technol. 2023. PMID: 37040126 Free PMC article. No abstract available.

7

Translating pharmacology models effectively to predict therapeutic benefit.

Dudal S, Bissantz C, Caruso A, David-Pierson P, Driessen W, Koller E, Krippendorff BF, Lechmann M, Olivares-Morales A, Paehler A, Rynn C, Türck D, Van De Vyver A, Wang K, Winther L. Dudal S, et al. Among authors: caruso a. Drug Discov Today. 2022 Jun;27(6):1604-1621. doi: 10.1016/j.drudis.2022.03.009. Epub 2022 Mar 15. Drug Discov Today. 2022. PMID: 35304340 Free article. Review.

8

RO6807936 as a novel positron emission tomography (PET) radiotracer for in vitro and in vivo visualization and quantification of beta-site amyloid precursor protein cleaving enzyme (BACE1) in the rodent and baboon brain.

Honer M, Polara A, Kuwabara H, Jacobsen H, Pähler A, Hartung T, Caruso A, Esterhazy D, Stoffel M, Dannals RF, Wong DF, Borroni E, Gobbi LC. Honer M, et al. Among authors: caruso a. J Labelled Comp Radiopharm. 2023 Jul;66(9):222-236. doi: 10.1002/jlcr.4025. Epub 2023 May 11. J Labelled Comp Radiopharm. 2023. PMID: 37095603

9

Correspondence.

Caruso A, Mazer NA. Caruso A, et al. Retina. 2020 Apr;40(4):e13. doi: 10.1097/IAE.0000000000002710. Retina. 2020. PMID: 31834136 Free PMC article. No abstract available.

10

Translational PK/PD modeling for cardiovascular safety assessment of drug candidates: Methods and examples in drug development.

Caruso A, Frances N, Meille C, Greiter-Wilke A, Hillebrecht A, Lavé T. Caruso A, et al. J Pharmacol Toxicol Methods. 2014 Jul-Aug;70(1):73-85. doi: 10.1016/j.vascn.2014.05.004. Epub 2014 May 28. J Pharmacol Toxicol Methods. 2014. PMID: 24879942

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