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CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease.
Djelti F, Braudeau J, Hudry E, Dhenain M, Varin J, Bièche I, Marquer C, Chali F, Ayciriex S, Auzeil N, Alves S, Langui D, Potier MC, Laprevote O, Vidaud M, Duyckaerts C, Miles R, Aubourg P, Cartier N. Djelti F, et al. Among authors: cartier n. Brain. 2015 Aug;138(Pt 8):2383-98. doi: 10.1093/brain/awv166. Epub 2015 Jul 2. Brain. 2015. PMID: 26141492
Alzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression.
Audrain M, Fol R, Dutar P, Potier B, Billard JM, Flament J, Alves S, Burlot MA, Dufayet-Chaffaud G, Bemelmans AP, Valette J, Hantraye P, Déglon N, Cartier N, Braudeau J. Audrain M, et al. Among authors: cartier n. Mol Neurodegener. 2016 Jan 12;11:5. doi: 10.1186/s13024-016-0070-y. Mol Neurodegener. 2016. PMID: 26759118 Free PMC article.
Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins.
Alves S, Marais T, Biferi MG, Furling D, Marinello M, El Hachimi K, Cartier N, Ruberg M, Stevanin G, Brice A, Barkats M, Sittler A. Alves S, et al. Among authors: cartier n. Mol Neurodegener. 2016 Jul 28;11(1):58. doi: 10.1186/s13024-016-0123-2. Mol Neurodegener. 2016. PMID: 27465358 Free PMC article.
93 results