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A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells In Vitro and Shows Antitumor Effects In Vivo.
Josa-Culleré L, Madden KS, Cogswell TJ, Jackson TR, Carter TS, Zhang D, Trevitt G, Davies SG, Vyas P, Wynne GM, Milne TA, Russell AJ. Josa-Culleré L, et al. Among authors: carter ts. J Med Chem. 2021 Nov 11;64(21):15608-15628. doi: 10.1021/acs.jmedchem.1c00574. Epub 2021 Oct 21. J Med Chem. 2021. PMID: 34672555 Free article.
Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines.
Josa-Culleré L, Galan SRG, Cogswell TJ, Jackson TR, Jay-Smith M, Mola L, Greaves CR, Carter TS, Madden KS, Trott S, Zhang D, Bataille CJR, Davies SG, Vyas P, Milne TA, Naylor A, Wynne GM, Russell AJ. Josa-Culleré L, et al. Among authors: carter ts. Eur J Med Chem. 2023 Oct 5;258:115509. doi: 10.1016/j.ejmech.2023.115509. Epub 2023 May 26. Eur J Med Chem. 2023. PMID: 37343464
Rate of atmospheric brown carbon whitening governed by environmental conditions.
Schnitzler EG, Gerrebos NGA, Carter TS, Huang Y, Heald CL, Bertram AK, Abbatt JPD. Schnitzler EG, et al. Among authors: carter ts. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2205610119. doi: 10.1073/pnas.2205610119. Epub 2022 Sep 12. Proc Natl Acad Sci U S A. 2022. PMID: 36095180 Free PMC article.
Microenvironmental sensing by fibroblasts controls macrophage population size.
Zhou X, Franklin RA, Adler M, Carter TS, Condiff E, Adams TS, Pope SD, Philip NH, Meizlish ML, Kaminski N, Medzhitov R. Zhou X, et al. Among authors: carter ts. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2205360119. doi: 10.1073/pnas.2205360119. Epub 2022 Aug 5. Proc Natl Acad Sci U S A. 2022. PMID: 35930670 Free PMC article.
A biomimetic receptor for glucose.
Tromans RA, Carter TS, Chabanne L, Crump MP, Li H, Matlock JV, Orchard MG, Davis AP. Tromans RA, et al. Among authors: carter ts. Nat Chem. 2019 Jan;11(1):52-56. doi: 10.1038/s41557-018-0155-z. Epub 2018 Nov 12. Nat Chem. 2019. PMID: 30420776
18 results