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Integrity profiling of high throughput screening hits using LC-MS and related techniques.
Kerns EH, Di L, Bourassa J, Gross J, Huang N, Liu H, Kleintop T, Nogle L, Mallis L, Petucci C, Petusky S, Tischler M, Sabus C, Sarkahian A, Young M, Zhang MY, Huryn D, McConnell O, Carter G. Kerns EH, et al. Comb Chem High Throughput Screen. 2005 Sep;8(6):459-66. doi: 10.2174/1386207054867283. Comb Chem High Throughput Screen. 2005. PMID: 16178805 Review.
In vitro solubility assays in drug discovery.
Kerns EH, Di L, Carter GT. Kerns EH, et al. Among authors: carter gt. Curr Drug Metab. 2008 Nov;9(9):879-85. doi: 10.2174/138920008786485100. Curr Drug Metab. 2008. PMID: 18991584 Review.
Drug-like property concepts in pharmaceutical design.
Di L, Kerns EH, Carter GT. Di L, et al. Among authors: carter gt. Curr Pharm Des. 2009;15(19):2184-94. doi: 10.2174/138161209788682479. Curr Pharm Des. 2009. PMID: 19601822 Review.
Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes.
McConnell O, Bach A 2nd, Balibar C, Byrne N, Cai Y, Carter G, Chlenov M, Di L, Fan K, Goljer I, He Y, Herold D, Kagan M, Kerns E, Koehn F, Kraml C, Marathias V, Marquez B, McDonald L, Nogle L, Petucci C, Schlingmann G, Tawa G, Tischler M, Williamson RT, Sutherland A, Watts W, Young M, Zhang MY, Zhang Y, Zhou D, Ho D. McConnell O, et al. Chirality. 2007 Sep;19(9):658-82. doi: 10.1002/chir.20399. Chirality. 2007. PMID: 17390370 Review.
Strategies to assess blood-brain barrier penetration.
Di L, Kerns EH, Carter GT. Di L, et al. Among authors: carter gt. Expert Opin Drug Discov. 2008 Jun;3(6):677-87. doi: 10.1517/17460441.3.6.677. Expert Opin Drug Discov. 2008. PMID: 23506148
289 results