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Mesoderm-derived PDGFRA+ cells regulate the emergence of hematopoietic stem cells in the dorsal aorta.
Chandrakanthan V, Rorimpandey P, Zanini F, Chacon D, Olivier J, Joshi S, Kang YC, Knezevic K, Huang Y, Qiao Q, Oliver RA, Unnikrishnan A, Carter DR, Lee B, Brownlee C, Power C, Brink R, Mendez-Ferrer S, Enikolopov G, Walsh W, Göttgens B, Taoudi S, Beck D, Pimanda JE. Chandrakanthan V, et al. Among authors: carter dr. Nat Cell Biol. 2022 Aug;24(8):1211-1225. doi: 10.1038/s41556-022-00955-3. Epub 2022 Jul 28. Nat Cell Biol. 2022. PMID: 35902769 Free PMC article.
Disruption of a GATA2-TAL1-ERG regulatory circuit promotes erythroid transition in healthy and leukemic stem cells.
Thoms JAI, Truong P, Subramanian S, Knezevic K, Harvey G, Huang Y, Seneviratne JA, Carter DR, Joshi S, Skhinas J, Chacon D, Shah A, de Jong I, Beck D, Göttgens B, Larsson J, Wong JWH, Zanini F, Pimanda JE. Thoms JAI, et al. Among authors: carter dr. Blood. 2021 Oct 21;138(16):1441-1455. doi: 10.1182/blood.2020009707. Blood. 2021. PMID: 34075404 Free article.
Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma.
Zhai L, Balachandran A, Larkin R, Seneviratne JA, Chung SA, Lalwani A, Tsubota S, Beck D, Kadomatsu K, Beckers A, Durink K, De Preter K, Speleman F, Haber M, Norris MD, Swarbrick A, Cheung BB, Marshall GM, Carter DR. Zhai L, et al. Among authors: carter dr. Int J Mol Sci. 2023 Oct 25;24(21):15571. doi: 10.3390/ijms242115571. Int J Mol Sci. 2023. PMID: 37958555 Free PMC article.
Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia.
Van Thillo Q, De Bie J, Seneviratne JA, Demeyer S, Omari S, Balachandran A, Zhai V, Tam WL, Sweron B, Geerdens E, Gielen O, Provost S, Segers H, Boeckx N, Marshall GM, Cheung BB, Isobe K, Kato I, Takita J, Amos TG, Deveson IW, McCalmont H, Lock RB, Oxley EP, Garwood MM, Dickins RA, Uyttebroeck A, Carter DR, Cools J, de Bock CE. Van Thillo Q, et al. Among authors: carter dr. Nat Commun. 2021 Jul 6;12(1):4164. doi: 10.1038/s41467-021-24442-9. Nat Commun. 2021. PMID: 34230493 Free PMC article.
Single-cell profiling of peripheral neuroblastic tumors identifies an aggressive transitional state that bridges an adrenergic-mesenchymal trajectory.
Yuan X, Seneviratne JA, Du S, Xu Y, Chen Y, Jin Q, Jin X, Balachandran A, Huang S, Xu Y, Zhai Y, Lu L, Tang M, Dong Y, Cheung BB, Marshall GM, Shi W, Carter DR, Zhang C. Yuan X, et al. Among authors: carter dr. Cell Rep. 2022 Oct 4;41(1):111455. doi: 10.1016/j.celrep.2022.111455. Cell Rep. 2022. PMID: 36198269 Free article.
The prenatal origins of cancer.
Marshall GM, Carter DR, Cheung BB, Liu T, Mateos MK, Meyerowitz JG, Weiss WA. Marshall GM, et al. Among authors: carter dr. Nat Rev Cancer. 2014 Apr;14(4):277-89. doi: 10.1038/nrc3679. Epub 2014 Mar 6. Nat Rev Cancer. 2014. PMID: 24599217 Free PMC article. Review.
A novel combination therapy targeting ubiquitin-specific protease 5 in MYCN-driven neuroblastoma.
Cheung BB, Kleynhans A, Mittra R, Kim PY, Holien JK, Nagy Z, Ciampa OC, Seneviratne JA, Mayoh C, Raipuria M, Gadde S, Massudi H, Wong IPL, Tan O, Gong A, Suryano A, Diakiw SM, Liu B, Arndt GM, Liu T, Kumar N, Sangfelt O, Zhu S, Norris MD, Haber M, Carter DR, Parker MW, Marshall GM. Cheung BB, et al. Among authors: carter dr. Oncogene. 2021 Apr;40(13):2367-2381. doi: 10.1038/s41388-021-01712-w. Epub 2021 Mar 3. Oncogene. 2021. PMID: 33658627 Free PMC article.
305 results