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Engineering of conotoxins for the treatment of pain.
Carstens BB, Clark RJ, Daly NL, Harvey PJ, Kaas Q, Craik DJ. Carstens BB, et al. Curr Pharm Des. 2011 Dec;17(38):4242-53. doi: 10.2174/138161211798999401. Curr Pharm Des. 2011. PMID: 22204425 Review.
Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABA(B) Receptor Activation Reveal a Minimal Functional Motif.
Carstens BB, Berecki G, Daniel JT, Lee HS, Jackson KA, Tae HS, Sadeghi M, Castro J, O'Donnell T, Deiteren A, Brierley SM, Craik DJ, Adams DJ, Clark RJ. Carstens BB, et al. Angew Chem Int Ed Engl. 2016 Apr 4;55(15):4692-6. doi: 10.1002/anie.201600297. Epub 2016 Mar 7. Angew Chem Int Ed Engl. 2016. PMID: 26948522
Structure-Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by α-Conotoxin Vc1.1.
Sadeghi M, Carstens BB, Callaghan BP, Daniel JT, Tae HS, O'Donnell T, Castro J, Brierley SM, Adams DJ, Craik DJ, Clark RJ. Sadeghi M, et al. Among authors: carstens bb. ACS Chem Biol. 2018 Jun 15;13(6):1577-1587. doi: 10.1021/acschembio.8b00190. Epub 2018 May 25. ACS Chem Biol. 2018. PMID: 29746088