Carruthers N - Search Results

1

IGF2BP1 regulates the cargo of extracellular vesicles and promotes neuroblastoma metastasis.

Dhamdhere MR, Gowda CP, Singh V, Liu Z, Carruthers N, Grant CN, Sharma A, Dovat S, Sundstrom JM, Wang HG, Spiegelman VS. Dhamdhere MR, et al. Among authors: carruthers n. Oncogene. 2023 May;42(19):1558-1571. doi: 10.1038/s41388-023-02671-0. Epub 2023 Mar 27. Oncogene. 2023. PMID: 36973517 Free PMC article.

2

Mass Spectrometry-Based Vitreous Proteomics: Validated Methods and Analysis Pipeline.

Weber S, Carruthers N, Gates C, Zhao Y, Sundstrom J. Weber S, et al. Among authors: carruthers n. Methods Mol Biol. 2023;2678:157-167. doi: 10.1007/978-1-0716-3255-0_11. Methods Mol Biol. 2023. PMID: 37326711

3

Extracellular vesicles from retinal pigment epithelial cells expressing R345W-Fibulin-3 induce epithelial-mesenchymal transition in recipient cells.

Zhou M, Zhao Y, Weber SR, Gates C, Carruthers NJ, Chen H, Liu X, Wang HG, Ford M, Swulius MT, Barber AJ, Grillo SL, Sundstrom JM. Zhou M, et al. Among authors: carruthers nj. J Extracell Vesicles. 2023 Oct;12(10):e12373. doi: 10.1002/jev2.12373. J Extracell Vesicles. 2023. PMID: 37855063 Free PMC article.

4

Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation.

Dorel R, Sun D, Carruthers N, Castanedo GM, Ung PM, Factor DC, Li T, Baumann H, Janota D, Pang J, Salphati L, Meklemburg R, Korman AJ, Harper HE, Stubblefield S, Payandeh J, McHugh D, Lang BT, Tesar PJ, Dere E, Masureel M, Adams DJ, Volgraf M, Braun MG. Dorel R, et al. Among authors: carruthers n. J Med Chem. 2024 Mar 28;67(6):4819-4832. doi: 10.1021/acs.jmedchem.3c02396. Epub 2024 Mar 12. J Med Chem. 2024. PMID: 38470227

5

Mercury intoxication disrupts tonic signaling in B cells, and may promote autoimmunity due to abnormal phosphorylation of STIM-1 and other autoimmunity risk associated phosphoproteins involved in BCR signaling.

Carruthers NJ, Guo C, Gill R, Stemmer PM, Rosenspire AJ. Carruthers NJ, et al. Toxicol Appl Pharmacol. 2023 Sep 1;474:116607. doi: 10.1016/j.taap.2023.116607. Epub 2023 Jun 20. Toxicol Appl Pharmacol. 2023. PMID: 37348680

6

Activation of Ca²⁺ transport in cardiac microsomes enriches functional sets of ER and SR proteins.

Cala SE, Carruthers NJ, Stemmer PM, Chen Z, Chen X. Cala SE, et al. Among authors: carruthers nj. Mol Cell Biochem. 2024 Jan;479(1):85-98. doi: 10.1007/s11010-023-04708-0. Epub 2023 Apr 10. Mol Cell Biochem. 2024. PMID: 37036634 Free PMC article.

7

Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease.

Vicente-Rodríguez M, Mancuso R, Peris-Yague A, Simmons C; NIMA Consortium; Gómez-Nicola D, Perry VH, Turkheimer F, Lovestone S, Parker CA, Cash D. Vicente-Rodríguez M, et al. J Neuroinflammation. 2023 Apr 9;20(1):92. doi: 10.1186/s12974-023-02769-y. J Neuroinflammation. 2023. PMID: 37032328 Free PMC article.

8

Activation of Ca transport in cardiac microsomes enriches functional sets of ER and SR proteins.

Cala SE, Carruthers NJ, Stemmer PM, Chen Z, Chen X. Cala SE, et al. Among authors: carruthers nj. Res Sq [Preprint]. 2023 Feb 8:rs.3.rs-2557992. doi: 10.21203/rs.3.rs-2557992/v1. Res Sq. 2023. PMID: 36798315 Free PMC article. Updated. Preprint.

9

Discovery of a Series of Substituted 1H-((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators.

Gelin CF, Stenne B, Coate H, Hiscox A, Soyode-Johnson A, Wall JL, Lord B, Schoellerman J, Coe KJ, Wang K, Alcázar J, Chrovian CC, Dvorak CA, Carruthers NI, Koudriakova T, Balana B, Letavic MA. Gelin CF, et al. Among authors: carruthers ni. J Med Chem. 2023 Feb 23;66(4):2877-2892. doi: 10.1021/acs.jmedchem.2c01916. Epub 2023 Feb 9. J Med Chem. 2023. PMID: 36757100

10

Deletion of mdig enhances H3K36me3 and metastatic potential of the triple negative breast cancer cells.

Thakur C, Qiu Y, Zhang Q, Carruthers NJ, Yu M, Bi Z, Fu Y, Wadgaonkar P, Almutairy B, Seno A, Stemmer PM, Chen F. Thakur C, et al. Among authors: carruthers nj. iScience. 2022 Sep 3;25(10):105057. doi: 10.1016/j.isci.2022.105057. eCollection 2022 Oct 21. iScience. 2022. PMID: 36124233 Free PMC article.

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