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Nucleophilic covalent ligand discovery for the cysteine redoxome.
Fu L, Jung Y, Tian C, Ferreira RB, Cheng R, He F, Yang J, Carroll KS. Fu L, et al. Among authors: carroll ks. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29. Nat Chem Biol. 2023. PMID: 37248412
Chaperone-directed ribosome repair after oxidative damage.
Yang YM, Jung Y, Abegg D, Adibekian A, Carroll KS, Karbstein K. Yang YM, et al. Among authors: carroll ks. Mol Cell. 2023 May 4;83(9):1527-1537.e5. doi: 10.1016/j.molcel.2023.03.030. Epub 2023 Apr 21. Mol Cell. 2023. PMID: 37086725 Free PMC article.
Neurologic Manifestations of Long COVID Differ Based on Acute COVID-19 Severity.
Perez Giraldo GS, Ali ST, Kang AK, Patel TR, Budhiraja S, Gaelen JI, Lank GK, Clark JR, Mukherjee S, Singer T, Venkatesh A, Orban ZS, Lim PH, Jimenez M, Miller J, Taylor C, Szymanski AL, Scarpelli J, Graham EL, Balabanov RD, Barcelo BE, Cahan JG, Ruckman K, Shepard AG, Slutzky MW, LaFaver K, Kumthekar PU, Shetty NK, Carroll KS, Ho SU, Lukas RV, Batra A, Liotta EM, Koralnik IJ. Perez Giraldo GS, et al. Among authors: carroll ks. Ann Neurol. 2023 Jul;94(1):146-159. doi: 10.1002/ana.26649. Epub 2023 Apr 19. Ann Neurol. 2023. PMID: 36966460
An increase in surface hydrophobicity mediates chaperone activity in N-chlorinated RidA.
Varatnitskaya M, Fasel J, Müller A, Lupilov N, Shi Y, Fuchs K, Krewing M, Jung C, Jacob T, Sitek B, Bandow JE, Carroll KS, Hofmann E, Leichert LI. Varatnitskaya M, et al. Among authors: carroll ks. Redox Biol. 2022 Jul;53:102332. doi: 10.1016/j.redox.2022.102332. Epub 2022 May 7. Redox Biol. 2022. PMID: 35598378 Free PMC article.
Thiol-based chemical probes exhibit antiviral activity against SARS-CoV-2 via allosteric disulfide disruption in the spike glycoprotein.
Shi Y, Zeida A, Edwards CE, Mallory ML, Sastre S, Machado MR, Pickles RJ, Fu L, Liu K, Yang J, Baric RS, Boucher RC, Radi R, Carroll KS. Shi Y, et al. Among authors: carroll ks. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2120419119. doi: 10.1073/pnas.2120419119. Proc Natl Acad Sci U S A. 2022. PMID: 35074895 Free PMC article.
96 results