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mTORC1 activity is supported by spatial association with focal adhesions.
Rabanal-Ruiz Y, Byron A, Wirth A, Madsen R, Sedlackova L, Hewitt G, Nelson G, Stingele J, Wills JC, Zhang T, Zeug A, Fässler R, Vanhaesebroeck B, Maddocks ODK, Ponimaskin E, Carroll B, Korolchuk VI. Rabanal-Ruiz Y, et al. Among authors: carroll b. J Cell Biol. 2021 May 3;220(5):e202004010. doi: 10.1083/jcb.202004010. J Cell Biol. 2021. PMID: 33635313 Free PMC article.
Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease.
Sarkar S, Carroll B, Buganim Y, Maetzel D, Ng AH, Cassady JP, Cohen MA, Chakraborty S, Wang H, Spooner E, Ploegh H, Gsponer J, Korolchuk VI, Jaenisch R. Sarkar S, et al. Among authors: carroll b. Cell Rep. 2013 Dec 12;5(5):1302-15. doi: 10.1016/j.celrep.2013.10.042. Epub 2013 Nov 27. Cell Rep. 2013. PMID: 24290752 Free PMC article.
Dual proteolytic pathways govern glycolysis and immune competence.
Lu W, Zhang Y, McDonald DO, Jing H, Carroll B, Robertson N, Zhang Q, Griffin H, Sanderson S, Lakey JH, Morgan NV, Reynard LN, Zheng L, Murdock HM, Turvey SE, Hackett SJ, Prestidge T, Hall JM, Cant AJ, Matthews HF, Koref MF, Simon AK, Korolchuk VI, Lenardo MJ, Hambleton S, Su HC. Lu W, et al. Among authors: carroll b. Cell. 2014 Dec 18;159(7):1578-90. doi: 10.1016/j.cell.2014.12.001. Cell. 2014. PMID: 25525876 Free PMC article.
Autophagy, lipophagy and lysosomal lipid storage disorders.
Ward C, Martinez-Lopez N, Otten EG, Carroll B, Maetzel D, Singh R, Sarkar S, Korolchuk VI. Ward C, et al. Among authors: carroll b. Biochim Biophys Acta. 2016 Apr;1861(4):269-84. doi: 10.1016/j.bbalip.2016.01.006. Epub 2016 Jan 14. Biochim Biophys Acta. 2016. PMID: 26778751 Free article. Review.
Mitochondria are required for pro-ageing features of the senescent phenotype.
Correia-Melo C, Marques FD, Anderson R, Hewitt G, Hewitt R, Cole J, Carroll BM, Miwa S, Birch J, Merz A, Rushton MD, Charles M, Jurk D, Tait SW, Czapiewski R, Greaves L, Nelson G, Bohlooly-Y M, Rodriguez-Cuenca S, Vidal-Puig A, Mann D, Saretzki G, Quarato G, Green DR, Adams PD, von Zglinicki T, Korolchuk VI, Passos JF. Correia-Melo C, et al. EMBO J. 2016 Apr 1;35(7):724-42. doi: 10.15252/embj.201592862. Epub 2016 Feb 4. EMBO J. 2016. PMID: 26848154 Free PMC article.
SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair.
Hewitt G, Carroll B, Sarallah R, Correia-Melo C, Ogrodnik M, Nelson G, Otten EG, Manni D, Antrobus R, Morgan BA, von Zglinicki T, Jurk D, Seluanov A, Gorbunova V, Johansen T, Passos JF, Korolchuk VI. Hewitt G, et al. Among authors: carroll b. Autophagy. 2016 Oct 2;12(10):1917-1930. doi: 10.1080/15548627.2016.1210368. Epub 2016 Jul 8. Autophagy. 2016. PMID: 27391408 Free PMC article.
Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?
Korolchuk VI, Miwa S, Carroll B, von Zglinicki T. Korolchuk VI, et al. Among authors: carroll b. EBioMedicine. 2017 Jul;21:7-13. doi: 10.1016/j.ebiom.2017.03.020. Epub 2017 Mar 14. EBioMedicine. 2017. PMID: 28330601 Free PMC article. Review.
1,005 results