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Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors α/γ agonists.
Carrieri A, Giudici M, Parente M, De Rosas M, Piemontese L, Fracchiolla G, Laghezza A, Tortorella P, Carbonara G, Lavecchia A, Gilardi F, Crestani M, Loiodice F. Carrieri A, et al. Eur J Med Chem. 2013 May;63:321-32. doi: 10.1016/j.ejmech.2013.02.015. Epub 2013 Feb 24. Eur J Med Chem. 2013. PMID: 23502212
Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor α/γ ligand LT175.
Piemontese L, Fracchiolla G, Carrieri A, Parente M, Laghezza A, Carbonara G, Sblano S, Tauro M, Gilardi F, Tortorella P, Lavecchia A, Crestani M, Desvergne B, Loiodice F. Piemontese L, et al. Among authors: carrieri a. Eur J Med Chem. 2015 Jan 27;90:583-94. doi: 10.1016/j.ejmech.2014.11.044. Epub 2014 Nov 24. Eur J Med Chem. 2015. PMID: 25497132
Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease.
Purgatorio R, de Candia M, Catto M, Carrieri A, Pisani L, De Palma A, Toma M, Ivanova OA, Voskressensky LG, Altomare CD. Purgatorio R, et al. Among authors: carrieri a. Eur J Med Chem. 2019 Sep 1;177:414-424. doi: 10.1016/j.ejmech.2019.05.062. Epub 2019 May 28. Eur J Med Chem. 2019. PMID: 31158754
Scouting around 1,2,3,4-Tetrahydrochromeno[3,2-c]pyridin-10-ones for Single- and Multitarget Ligands Directed towards Relevant Alzheimer's Targets.
Purgatorio R, Kulikova LN, Pisani L, Catto M, de Candia M, Carrieri A, Cellamare S, De Palma A, Beloglazkin AA, Reza Raesi G, Voskressensky LG, Altomare CD. Purgatorio R, et al. Among authors: carrieri a. ChemMedChem. 2020 Oct 19;15(20):1947-1955. doi: 10.1002/cmdc.202000468. Epub 2020 Sep 4. ChemMedChem. 2020. PMID: 32716595
A New Series of Aryloxyacetic Acids Endowed with Multi-Target Activity towards Peroxisome Proliferator-Activated Receptors (PPARs), Fatty Acid Amide Hydrolase (FAAH), and Acetylcholinesterase (AChE).
Leuci R, Brunetti L, Laghezza A, Piemontese L, Carrieri A, Pisani L, Tortorella P, Catto M, Loiodice F. Leuci R, et al. Among authors: carrieri a. Molecules. 2022 Jan 31;27(3):958. doi: 10.3390/molecules27030958. Molecules. 2022. PMID: 35164223 Free PMC article.
Structure-based design of novel donepezil-like hybrids for a multi-target approach to the therapy of Alzheimer's disease.
Brunetti L, Leuci R, Carrieri A, Catto M, Occhineri S, Vinci G, Gambacorta L, Baltrukevich H, Chaves S, Laghezza A, Altomare CD, Tortorella P, Santos MA, Loiodice F, Piemontese L. Brunetti L, et al. Among authors: carrieri a. Eur J Med Chem. 2022 Jul 5;237:114358. doi: 10.1016/j.ejmech.2022.114358. Epub 2022 Apr 14. Eur J Med Chem. 2022. PMID: 35462163
Novel Phenothiazine/Donepezil-like Hybrids Endowed with Antioxidant Activity for a Multi-Target Approach to the Therapy of Alzheimer's Disease.
Carocci A, Barbarossa A, Leuci R, Carrieri A, Brunetti L, Laghezza A, Catto M, Limongelli F, Chaves S, Tortorella P, Altomare CD, Santos MA, Loiodice F, Piemontese L. Carocci A, et al. Among authors: carrieri a. Antioxidants (Basel). 2022 Aug 23;11(9):1631. doi: 10.3390/antiox11091631. Antioxidants (Basel). 2022. PMID: 36139705 Free PMC article.
2-Aminobenzothiazole derivatives: search for new antifungal agents.
Catalano A, Carocci A, Defrenza I, Muraglia M, Carrieri A, Van Bambeke F, Rosato A, Corbo F, Franchini C. Catalano A, et al. Among authors: carrieri a. Eur J Med Chem. 2013 Jun;64:357-64. doi: 10.1016/j.ejmech.2013.03.064. Epub 2013 Apr 9. Eur J Med Chem. 2013. PMID: 23644218 Free article.
149 results