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PML hyposumoylation is responsible for the resistance of pancreatic cancer.
Swayden M, Alzeeb G, Masoud R, Berthois Y, Audebert S, Camoin L, Hannouche L, Vachon H, Gayet O, Bigonnet M, Roques J, Silvy F, Carrier A, Dusetti N, Iovanna JL, Soubeyran P. Swayden M, et al. Among authors: carrier a. FASEB J. 2019 Nov;33(11):12447-12463. doi: 10.1096/fj.201901091R. Epub 2019 Sep 16. FASEB J. 2019. PMID: 31557059 Free PMC article.
Importantly, using patient-derived tumors and cell lines, we identified a correlation between the levels of PML expression and sumoylation and the sensitivity of tumors to anticancer treatments.-Swayden, M., Alzeeb, G., Masoud, R., Berthois, Y., Audebert, S., Camoin, L., H …
Importantly, using patient-derived tumors and cell lines, we identified a correlation between the levels of PML expression and sumoyl …
Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development.
Gironella M, Seux M, Xie MJ, Cano C, Tomasini R, Gommeaux J, Garcia S, Nowak J, Yeung ML, Jeang KT, Chaix A, Fazli L, Motoo Y, Wang Q, Rocchi P, Russo A, Gleave M, Dagorn JC, Iovanna JL, Carrier A, Pébusque MJ, Dusetti NJ. Gironella M, et al. Among authors: carrier a. Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16170-5. doi: 10.1073/pnas.0703942104. Epub 2007 Oct 2. Proc Natl Acad Sci U S A. 2007. PMID: 17911264 Free PMC article.
Absence of tumor suppressor tumor protein 53-induced nuclear protein 1 (TP53INP1) sensitizes mouse thymocytes and embryonic fibroblasts to redox-driven apoptosis.
N'guessan P, Pouyet L, Gosset G, Hamlaoui S, Seillier M, Cano CE, Seux M, Stocker P, Culcasi M, Iovanna JL, Dusetti NJ, Pietri S, Carrier A. N'guessan P, et al. Among authors: carrier a. Antioxid Redox Signal. 2011 Sep 15;15(6):1639-53. doi: 10.1089/ars.2010.3553. Epub 2011 May 5. Antioxid Redox Signal. 2011. PMID: 21235351
TP53INP1 decreases pancreatic cancer cell migration by regulating SPARC expression.
Seux M, Peuget S, Montero MP, Siret C, Rigot V, Clerc P, Gigoux V, Pellegrino E, Pouyet L, N'Guessan P, Garcia S, Dufresne M, Iovanna JL, Carrier A, André F, Dusetti NJ. Seux M, et al. Among authors: carrier a. Oncogene. 2011 Jul 7;30(27):3049-61. doi: 10.1038/onc.2011.25. Epub 2011 Feb 21. Oncogene. 2011. PMID: 21339733
165 results