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Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases.
Loaëc N, Attanasio E, Villiers B, Durieu E, Tahtouh T, Cam M, Davis RA, Alencar A, Roué M, Bourguet-Kondracki ML, Proksch P, Limanton E, Guiheneuf S, Carreaux F, Bazureau JP, Klautau M, Meijer L. Loaëc N, et al. Among authors: carreaux f. Mar Drugs. 2017 Oct 17;15(10):316. doi: 10.3390/md15100316. Mar Drugs. 2017. PMID: 29039762 Free PMC article. Review.
Leucettines, a class of potent inhibitors of cdc2-like kinases and dual specificity, tyrosine phosphorylation regulated kinases derived from the marine sponge leucettamine B: modulation of alternative pre-RNA splicing.
Debdab M, Carreaux F, Renault S, Soundararajan M, Fedorov O, Filippakopoulos P, Lozach O, Babault L, Tahtouh T, Baratte B, Ogawa Y, Hagiwara M, Eisenreich A, Rauch U, Knapp S, Meijer L, Bazureau JP. Debdab M, et al. Among authors: carreaux f. J Med Chem. 2011 Jun 23;54(12):4172-86. doi: 10.1021/jm200274d. Epub 2011 May 26. J Med Chem. 2011. PMID: 21615147
An efficient approach to dispacamide A and its derivatives.
Guihéneuf S, Paquin L, Carreaux F, Durieu E, Meijer L, Bazureau JP. Guihéneuf S, et al. Among authors: carreaux f. Org Biomol Chem. 2012 Feb 7;10(5):978-87. doi: 10.1039/c1ob06161e. Epub 2011 Dec 8. Org Biomol Chem. 2012. PMID: 22159215
Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B.
Tahtouh T, Elkins JM, Filippakopoulos P, Soundararajan M, Burgy G, Durieu E, Cochet C, Schmid RS, Lo DC, Delhommel F, Oberholzer AE, Pearl LH, Carreaux F, Bazureau JP, Knapp S, Meijer L. Tahtouh T, et al. Among authors: carreaux f. J Med Chem. 2012 Nov 8;55(21):9312-30. doi: 10.1021/jm301034u. Epub 2012 Oct 8. J Med Chem. 2012. PMID: 22998443
cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease.
Fant X, Durieu E, Chicanne G, Payrastre B, Sbrissa D, Shisheva A, Limanton E, Carreaux F, Bazureau JP, Meijer L. Fant X, et al. Among authors: carreaux f. Mol Pharmacol. 2014 Mar;85(3):441-50. doi: 10.1124/mol.113.090837. Epub 2013 Dec 23. Mol Pharmacol. 2014. PMID: 24366666 Free PMC article.
New 5-ylidene rhodanine derivatives based on the dispacamide A model.
Guiheneuf S, Paquin L, Carreaux F, Durieu E, Roisnel T, Meijer L, Bazureau JP. Guiheneuf S, et al. Among authors: carreaux f. Mol Divers. 2014 May;18(2):375-88. doi: 10.1007/s11030-014-9509-7. Epub 2014 Mar 2. Mol Divers. 2014. PMID: 24584455 Free article.
48 results