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Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma.
Carrabotta M, Laginestra MA, Durante G, Mancarella C, Landuzzi L, Parra A, Ruzzi F, Toracchio L, De Feo A, Giusti V, Pasello M, Righi A, Lollini PL, Palmerini E, Donati DM, Manara MC, Scotlandi K. Carrabotta M, et al. Cancer Res. 2022 Feb 15;82(4):708-720. doi: 10.1158/0008-5472.CAN-21-1222. Cancer Res. 2022. PMID: 34903601 Free PMC article.
Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations.
Nanni P, Landuzzi L, Manara MC, Righi A, Nicoletti G, Cristalli C, Pasello M, Parra A, Carrabotta M, Ferracin M, Palladini A, Ianzano ML, Giusti V, Ruzzi F, Magnani M, Donati DM, Picci P, Lollini PL, Scotlandi K. Nanni P, et al. Among authors: carrabotta m. Sci Rep. 2019 Aug 21;9(1):12174. doi: 10.1038/s41598-019-48634-y. Sci Rep. 2019. PMID: 31434953 Free PMC article.
ROCK2 deprivation leads to the inhibition of tumor growth and metastatic potential in osteosarcoma cells through the modulation of YAP activity.
Zucchini C, Manara MC, Cristalli C, Carrabotta M, Greco S, Pinca RS, Ferrari C, Landuzzi L, Pasello M, Lollini PL, Gambarotti M, Donati DM, Scotlandi K. Zucchini C, et al. Among authors: carrabotta m. J Exp Clin Cancer Res. 2019 Dec 26;38(1):503. doi: 10.1186/s13046-019-1506-3. J Exp Clin Cancer Res. 2019. PMID: 31878963 Free PMC article.
Engagement of CD99 Activates Distinct Programs in Ewing Sarcoma and Macrophages.
Manara MC, Manferdini C, Cristalli C, Carrabotta M, Santi S, De Feo A, Caldoni G, Pasello M, Landuzzi L, Lollini PL, Salamanna F, Dominici S, Fiori V, Magnani M, Lisignoli G, Scotlandi K. Manara MC, et al. Among authors: carrabotta m. Cancer Immunol Res. 2024 Feb 2;12(2):247-260. doi: 10.1158/2326-6066.CIR-23-0440. Cancer Immunol Res. 2024. PMID: 38051221 Free PMC article.