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Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes.
Lopez CA, Al-Siddiqi HHAA, Purnama U, Iftekhar S, Bruyneel AAN, Kerr M, Nazir R, da Luz Sousa Fialho M, Malandraki-Miller S, Alonaizan R, Kermani F, Heather LC, Czernuszka J, Carr CA. Lopez CA, et al. Among authors: carr ca. Sci Rep. 2021 Apr 8;11(1):7802. doi: 10.1038/s41598-021-87186-y. Sci Rep. 2021. PMID: 33833285 Free PMC article.
Investigating mitochondrial metabolism in contracting HL-1 cardiomyocytes following hypoxia and pharmacological HIF activation identifies HIF-dependent and independent mechanisms of regulation.
Ambrose LJ, Abd-Jamil AH, Gomes RS, Carter EE, Carr CA, Clarke K, Heather LC. Ambrose LJ, et al. Among authors: carr ca. J Cardiovasc Pharmacol Ther. 2014 Nov;19(6):574-85. doi: 10.1177/1074248414524480. Epub 2014 Mar 7. J Cardiovasc Pharmacol Ther. 2014. PMID: 24607765
Preconditioning of Cardiosphere-Derived Cells With Hypoxia or Prolyl-4-Hydroxylase Inhibitors Increases Stemness and Decreases Reliance on Oxidative Metabolism.
Tan SC, Gomes RS, Yeoh KK, Perbellini F, Malandraki-Miller S, Ambrose L, Heather LC, Faggian G, Schofield CJ, Davies KE, Clarke K, Carr CA. Tan SC, et al. Among authors: carr ca. Cell Transplant. 2016;25(1):35-53. doi: 10.3727/096368915X687697. Epub 2015 Mar 6. Cell Transplant. 2016. PMID: 25751158 Free PMC article.
Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation.
Mansor LS, Mehta K, Aksentijevic D, Carr CA, Lund T, Cole MA, Le Page L, Sousa Fialho Mda L, Shattock MJ, Aasum E, Clarke K, Tyler DJ, Heather LC. Mansor LS, et al. Among authors: carr ca. J Physiol. 2016 Jan 15;594(2):307-20. doi: 10.1113/JP271242. Epub 2015 Dec 20. J Physiol. 2016. PMID: 26574233 Free PMC article.
111 results