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A human memory T cell subset with stem cell-like properties.
Gattinoni L, Lugli E, Ji Y, Pos Z, Paulos CM, Quigley MF, Almeida JR, Gostick E, Yu Z, Carpenito C, Wang E, Douek DC, Price DA, June CH, Marincola FM, Roederer M, Restifo NP. Gattinoni L, et al. Among authors: carpenito c. Nat Med. 2011 Sep 18;17(10):1290-7. doi: 10.1038/nm.2446. Nat Med. 2011. PMID: 21926977 Free PMC article.
Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.
Carpenito C, Milone MC, Hassan R, Simonet JC, Lakhal M, Suhoski MM, Varela-Rohena A, Haines KM, Heitjan DF, Albelda SM, Carroll RG, Riley JL, Pastan I, June CH. Carpenito C, et al. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3360-5. doi: 10.1073/pnas.0813101106. Epub 2009 Feb 11. Proc Natl Acad Sci U S A. 2009. PMID: 19211796 Free PMC article.
Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo.
Milone MC, Fish JD, Carpenito C, Carroll RG, Binder GK, Teachey D, Samanta M, Lakhal M, Gloss B, Danet-Desnoyers G, Campana D, Riley JL, Grupp SA, June CH. Milone MC, et al. Among authors: carpenito c. Mol Ther. 2009 Aug;17(8):1453-64. doi: 10.1038/mt.2009.83. Epub 2009 Apr 21. Mol Ther. 2009. PMID: 19384291 Free PMC article.
ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells.
Guedan S, Chen X, Madar A, Carpenito C, McGettigan SE, Frigault MJ, Lee J, Posey AD Jr, Scholler J, Scholler N, Bonneau R, June CH. Guedan S, et al. Among authors: carpenito c. Blood. 2014 Aug 14;124(7):1070-80. doi: 10.1182/blood-2013-10-535245. Epub 2014 Jul 1. Blood. 2014. PMID: 24986688 Free PMC article.
Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells.
Frigault MJ, Lee J, Basil MC, Carpenito C, Motohashi S, Scholler J, Kawalekar OU, Guedan S, McGettigan SE, Posey AD Jr, Ang S, Cooper LJ, Platt JM, Johnson FB, Paulos CM, Zhao Y, Kalos M, Milone MC, June CH. Frigault MJ, et al. Among authors: carpenito c. Cancer Immunol Res. 2015 Apr;3(4):356-67. doi: 10.1158/2326-6066.CIR-14-0186. Epub 2015 Jan 19. Cancer Immunol Res. 2015. PMID: 25600436 Free PMC article.
44 results