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Syrian hamster convalescence from prototype SARS-CoV-2 confers measurable protection against the attenuated disease caused by the Omicron variant.
Ryan KA, Bewley KR, Watson RJ, Burton C, Carnell O, Cavell BE, Challis A, Coombes NS, Davies ER, Edun-Huges J, Emery K, Fell R, Fotheringham SA, Gooch KE, Gowan K, Handley A, Harris DJ, Hesp R, Hunter L, Humphreys R, Johnson R, Kennard C, Knott D, Lister S, Morley D, Ngabo D, Osman KL, Paterson J, Penn EJ, Pullan ST, Richards KS, Summers S, Thomas SR, Weldon T, Wiblin NR, Rayner EL, Vipond RT, Hallis B, Salguero FJ, Funnell SGP, Hall Y. Ryan KA, et al. Among authors: carnell o. PLoS Pathog. 2023 Apr 4;19(4):e1011293. doi: 10.1371/journal.ppat.1011293. eCollection 2023 Apr. PLoS Pathog. 2023. PMID: 37014911 Free PMC article.
SARS-CoV-2 Disease Severity in the Golden Syrian Hamster Model of Infection Is Related to the Volume of Intranasal Inoculum.
Handley A, Ryan KA, Davies ER, Bewley KR, Carnell OT, Challis A, Coombes NS, Fotheringham SA, Gooch KE, Charlton M, Harris DJ, Kennard C, Ngabo D, Weldon TM, Salguero FJ, Funnell SGP, Hall Y. Handley A, et al. Among authors: carnell ot. Viruses. 2023 Mar 14;15(3):748. doi: 10.3390/v15030748. Viruses. 2023. PMID: 36992457 Free PMC article.
Development of a Hamster Natural Transmission Model of SARS-CoV-2 Infection.
Dowall S, Salguero FJ, Wiblin N, Fotheringham S, Hatch G, Parks S, Gowan K, Harris D, Carnell O, Fell R, Watson R, Graham V, Gooch K, Hall Y, Mizen S, Hewson R. Dowall S, et al. Among authors: carnell o. Viruses. 2021 Nov 9;13(11):2251. doi: 10.3390/v13112251. Viruses. 2021. PMID: 34835057 Free PMC article.
A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.
Huo J, Mikolajek H, Le Bas A, Clark JJ, Sharma P, Kipar A, Dormon J, Norman C, Weckener M, Clare DK, Harrison PJ, Tree JA, Buttigieg KR, Salguero FJ, Watson R, Knott D, Carnell O, Ngabo D, Elmore MJ, Fotheringham S, Harding A, Moynié L, Ward PN, Dumoux M, Prince T, Hall Y, Hiscox JA, Owen A, James W, Carroll MW, Stewart JP, Naismith JH, Owens RJ. Huo J, et al. Among authors: carnell o. Nat Commun. 2021 Sep 22;12(1):5469. doi: 10.1038/s41467-021-25480-z. Nat Commun. 2021. PMID: 34552091 Free PMC article.
Commensal bacteria augment Staphylococcus aureus infection by inactivation of phagocyte-derived reactive oxygen species.
Gibson JF, Pidwill GR, Carnell OT, Surewaard BGJ, Shamarina D, Sutton JAF, Jeffery C, Derré-Bobillot A, Archambaud C, Siggins MK, Pollitt EJG, Johnston SA, Serror P, Sriskandan S, Renshaw SA, Foster SJ. Gibson JF, et al. Among authors: carnell ot. PLoS Pathog. 2021 Sep 16;17(9):e1009880. doi: 10.1371/journal.ppat.1009880. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34529737 Free PMC article.
Staphylococcus aureus cell wall structure and dynamics during host-pathogen interaction.
Sutton JAF, Carnell OT, Lafage L, Gray J, Biboy J, Gibson JF, Pollitt EJG, Tazoll SC, Turnbull W, Hajdamowicz NH, Salamaga B, Pidwill GR, Condliffe AM, Renshaw SA, Vollmer W, Foster SJ. Sutton JAF, et al. Among authors: carnell ot. PLoS Pathog. 2021 Mar 31;17(3):e1009468. doi: 10.1371/journal.ppat.1009468. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33788901 Free PMC article.
Evolving MRSA: High-level β-lactam resistance in Staphylococcus aureus is associated with RNA Polymerase alterations and fine tuning of gene expression.
Panchal VV, Griffiths C, Mosaei H, Bilyk B, Sutton JAF, Carnell OT, Hornby DP, Green J, Hobbs JK, Kelley WL, Zenkin N, Foster SJ. Panchal VV, et al. Among authors: carnell ot. PLoS Pathog. 2020 Jul 24;16(7):e1008672. doi: 10.1371/journal.ppat.1008672. eCollection 2020 Jul. PLoS Pathog. 2020. PMID: 32706832 Free PMC article.