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The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity.
Stewart H, Lu Y, O'Keefe S, Valpadashi A, Cruz-Zaragoza LD, Michel HA, Nguyen SK, Carnell GW, Lukhovitskaya N, Milligan R, Adewusi Y, Jungreis I, Lulla V, Matthews DA, High S, Rehling P, Emmott E, Heeney JL, Davidson AD, Edgar JR, Smith GL, Firth AE. Stewart H, et al. Among authors: carnell gw. iScience. 2023 Sep 28;26(11):108080. doi: 10.1016/j.isci.2023.108080. eCollection 2023 Nov 17. iScience. 2023. PMID: 37860693 Free PMC article.
Tetherin antagonism by SARS-CoV-2 enhances virus release: multiple mechanisms including ORF3a-mediated defective retrograde traffic.
Stewart H, Palmulli R, Johansen KH, McGovern N, Shehata OM, Carnell GW, Jackson HK, Lee JS, Brown JC, Burgoyne T, Heeney JL, Okkenhaug K, Firth AE, Peden AA, Edgar JR. Stewart H, et al. Among authors: carnell gw. bioRxiv [Preprint]. 2022 Dec 22:2021.01.06.425396. doi: 10.1101/2021.01.06.425396. bioRxiv. 2022. PMID: 33442692 Free PMC article. Updated. Preprint.
SARS-CoV-2 Spike Protein Stabilized in the Closed State Induces Potent Neutralizing Responses.
Carnell GW, Ciazynska KA, Wells DA, Xiong X, Aguinam ET, McLaughlin SH, Mallery D, Ebrahimi S, Ceron-Gutierrez L, Asbach B, Einhauser S, Wagner R, James LC, Doffinger R, Heeney JL, Briggs JAG. Carnell GW, et al. J Virol. 2021 Jul 12;95(15):e0020321. doi: 10.1128/JVI.00203-21. Epub 2021 Jul 12. J Virol. 2021. PMID: 33963055 Free PMC article.
Critical Care Workers Have Lower Seroprevalence of SARS-CoV-2 IgG Compared with Non-patient Facing Staff in First Wave of COVID19.
Baxendale HE, Wells D, Gronlund J, Nadesalingham A, Paloniemi M, Carnell G, Tonks P, Ceron-Gutierrez L, Ebrahimi S, Sayer A, Briggs JAG, Ziong X, Nathan JA, Grice G, James LC, Luptak J, Pai S, Heeney JL, Lear S, Doffinger R. Baxendale HE, et al. J Crit Care Med (Targu Mures). 2021 Aug 5;7(3):199-210. doi: 10.2478/jccm-2021-0018. eCollection 2021 Jul. J Crit Care Med (Targu Mures). 2021. PMID: 34722923 Free PMC article.
Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases.
Castillo-Olivares J, Wells DA, Ferrari M, Chan ACY, Smith P, Nadesalingam A, Paloniemi M, Carnell GW, Ohlendorf L, Cantoni D, Mayora-Neto M, Palmer P, Tonks P, Temperton NJ, Peterhoff D, Neckermann P, Wagner R, Doffinger R, Kempster S, Otter AD, Semper A, Brooks T, Albecka A, James LC, Page M, Schwaeble W, Baxendale H, Heeney JL. Castillo-Olivares J, et al. Among authors: carnell gw. Front Immunol. 2021 Nov 19;12:748291. doi: 10.3389/fimmu.2021.748291. eCollection 2021. Front Immunol. 2021. PMID: 34867975 Free PMC article.
SARS-CoV-2 nucleocapsid protein adheres to replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress.
Scherer KM, Mascheroni L, Carnell GW, Wunderlich LCS, Makarchuk S, Brockhoff M, Mela I, Fernandez-Villegas A, Barysevich M, Stewart H, Suau Sans M, George CL, Lamb JR, Kaminski-Schierle GS, Heeney JL, Kaminski CF. Scherer KM, et al. Among authors: carnell gw. Sci Adv. 2022 Jan 7;8(1):eabl4895. doi: 10.1126/sciadv.abl4895. Epub 2022 Jan 7. Sci Adv. 2022. PMID: 34995113 Free PMC article.
AutoPlate: Rapid Dose-Response Curve Analysis for Biological Assays.
Palmer P, Del Rosario JMM, da Costa KAS, Carnell GW, Huang CQ, Heeney JL, Temperton NJ, Wells DA. Palmer P, et al. Among authors: carnell gw. Front Immunol. 2022 Feb 10;12:681636. doi: 10.3389/fimmu.2021.681636. eCollection 2021. Front Immunol. 2022. PMID: 35222351 Free PMC article.
Vaccination and protective immunity to SARS-CoV-2 omicron variants in people with immunodeficiencies.
Nadesalingam A, Cantoni D, Aguinam ET, Chan AC, Paloniemi M, Ohlendorf L, George C, Carnell G, Lyall J, Ferrari M, Temperton N, Wagner R, Castillo-Olivares J, Baxendale H, Heeney JL. Nadesalingam A, et al. Lancet Microbe. 2023 Feb;4(2):e58-e59. doi: 10.1016/S2666-5247(22)00297-X. Epub 2022 Nov 1. Lancet Microbe. 2023. PMID: 36332646 Free PMC article. No abstract available.
34 results