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Trypanosoma cruzi infection is enhanced by vector saliva through immunosuppressant mechanisms mediated by lysophosphatidylcholine.
Mesquita RD, Carneiro AB, Bafica A, Gazos-Lopes F, Takiya CM, Souto-Padron T, Vieira DP, Ferreira-Pereira A, Almeida IC, Figueiredo RT, Porto BN, Bozza MT, Graça-Souza AV, Lopes AH, Atella GC, Silva-Neto MA. Mesquita RD, et al. Among authors: carneiro ab. Infect Immun. 2008 Dec;76(12):5543-52. doi: 10.1128/IAI.00683-08. Epub 2008 Sep 15. Infect Immun. 2008. PMID: 18794282 Free PMC article.
Lysophosphatidylcholine triggers TLR2- and TLR4-mediated signaling pathways but counteracts LPS-induced NO synthesis in peritoneal macrophages by inhibiting NF-κB translocation and MAPK/ERK phosphorylation.
Carneiro AB, Iaciura BM, Nohara LL, Lopes CD, Veas EM, Mariano VS, Bozza PT, Lopes UG, Atella GC, Almeida IC, Silva-Neto MA. Carneiro AB, et al. PLoS One. 2013 Sep 30;8(9):e76233. doi: 10.1371/journal.pone.0076233. eCollection 2013. PLoS One. 2013. PMID: 24312681 Free PMC article.
Schistosomal-derived lysophosphatidylcholine triggers M2 polarization of macrophages through PPARγ dependent mechanisms.
Assunção LS, Magalhães KG, Carneiro AB, Molinaro R, Almeida PE, Atella GC, Castro-Faria-Neto HC, Bozza PT. Assunção LS, et al. Among authors: carneiro ab. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Feb;1862(2):246-254. doi: 10.1016/j.bbalip.2016.11.006. Epub 2016 Nov 15. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 27871882
Lipid Body Organelles within the Parasite Trypanosoma cruzi: A Role for Intracellular Arachidonic Acid Metabolism.
Toledo DA, Roque NR, Teixeira L, Milán-Garcés EA, Carneiro AB, Almeida MR, Andrade GF, Martins JS, Pinho RR, Freire-de-Lima CG, Bozza PT, D'Avila H, Melo RC. Toledo DA, et al. Among authors: carneiro ab. PLoS One. 2016 Aug 4;11(8):e0160433. doi: 10.1371/journal.pone.0160433. eCollection 2016. PLoS One. 2016. PMID: 27490663 Free PMC article.
Glycoinositolphospholipids from Trypanosomatids subvert nitric oxide production in Rhodnius prolixus salivary glands.
Gazos-Lopes F, Mesquita RD, Silva-Cardoso L, Senna R, Silveira AB, Jablonka W, Cudischevitch CO, Carneiro AB, Machado EA, Lima LG, Monteiro RQ, Nussenzveig RH, Folly E, Romeiro A, Vanbeselaere J, Mendonça-Previato L, Previato JO, Valenzuela JG, Ribeiro JM, Atella GC, Silva-Neto MA. Gazos-Lopes F, et al. Among authors: carneiro ab. PLoS One. 2012;7(10):e47285. doi: 10.1371/journal.pone.0047285. Epub 2012 Oct 15. PLoS One. 2012. PMID: 23077586 Free PMC article.
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