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Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes.
Zheng X, Narayanan S, Xu C, Eliasson Angelstig S, Grünler J, Zhao A, Di Toro A, Bernardi L, Mazzone M, Carmeliet P, Del Sole M, Solaini G, Forsberg EA, Zhang A, Brismar K, Schiffer TA, Rajamand Ekberg N, Botusan IR, Palm F, Catrina SB. Zheng X, et al. Among authors: carmeliet p. Elife. 2022 Feb 15;11:e70714. doi: 10.7554/eLife.70714. Elife. 2022. PMID: 35164902 Free PMC article.
Building in resistance to endothelial cell death.
Mazzone M, Ruiz de Almodovar C, Carmeliet P. Mazzone M, et al. Among authors: carmeliet p. Nat Genet. 2007 Nov;39(11):1308-9. doi: 10.1038/ng1107-1308. Nat Genet. 2007. PMID: 17968346 No abstract available.
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism.
Aragonés J, Schneider M, Van Geyte K, Fraisl P, Dresselaers T, Mazzone M, Dirkx R, Zacchigna S, Lemieux H, Jeoung NH, Lambrechts D, Bishop T, Lafuste P, Diez-Juan A, Harten SK, Van Noten P, De Bock K, Willam C, Tjwa M, Grosfeld A, Navet R, Moons L, Vandendriessche T, Deroose C, Wijeyekoon B, Nuyts J, Jordan B, Silasi-Mansat R, Lupu F, Dewerchin M, Pugh C, Salmon P, Mortelmans L, Gallez B, Gorus F, Buyse J, Sluse F, Harris RA, Gnaiger E, Hespel P, Van Hecke P, Schuit F, Van Veldhoven P, Ratcliffe P, Baes M, Maxwell P, Carmeliet P. Aragonés J, et al. Among authors: carmeliet p. Nat Genet. 2008 Feb;40(2):170-80. doi: 10.1038/ng.2007.62. Epub 2008 Jan 6. Nat Genet. 2008. PMID: 18176562 Free article.
Drug discovery: a lifeline for suffocating tissues.
Mazzone M, Carmeliet P. Mazzone M, et al. Among authors: carmeliet p. Nature. 2008 Jun 26;453(7199):1194-5. doi: 10.1038/4531194a. Nature. 2008. PMID: 18580938 No abstract available.
Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.
Mazzone M, Dettori D, de Oliveira RL, Loges S, Schmidt T, Jonckx B, Tian YM, Lanahan AA, Pollard P, de Almodovar CR, De Smet F, Vinckier S, Aragonés J, Debackere K, Luttun A, Wyns S, Jordan B, Pisacane A, Gallez B, Lampugnani MG, Dejana E, Simons M, Ratcliffe P, Maxwell P, Carmeliet P. Mazzone M, et al. Among authors: carmeliet p. Cell. 2009 Mar 6;136(5):839-851. doi: 10.1016/j.cell.2009.01.020. Epub 2009 Feb 12. Cell. 2009. PMID: 19217150 Free PMC article.
Regulation of angiogenesis by oxygen and metabolism.
Fraisl P, Mazzone M, Schmidt T, Carmeliet P. Fraisl P, et al. Among authors: carmeliet p. Dev Cell. 2009 Feb;16(2):167-79. doi: 10.1016/j.devcel.2009.01.003. Dev Cell. 2009. PMID: 19217420 Free article. Review.
Role and therapeutic potential of VEGF in the nervous system.
Ruiz de Almodovar C, Lambrechts D, Mazzone M, Carmeliet P. Ruiz de Almodovar C, et al. Among authors: carmeliet p. Physiol Rev. 2009 Apr;89(2):607-48. doi: 10.1152/physrev.00031.2008. Physiol Rev. 2009. PMID: 19342615 Free article. Review.
Impaired autonomic regulation of resistance arteries in mice with low vascular endothelial growth factor or upon vascular endothelial growth factor trap delivery.
Storkebaum E, Ruiz de Almodovar C, Meens M, Zacchigna S, Mazzone M, Vanhoutte G, Vinckier S, Miskiewicz K, Poesen K, Lambrechts D, Janssen GM, Fazzi GE, Verstreken P, Haigh J, Schiffers PM, Rohrer H, Van der Linden A, De Mey JG, Carmeliet P. Storkebaum E, et al. Among authors: carmeliet p. Circulation. 2010 Jul 20;122(3):273-81. doi: 10.1161/CIRCULATIONAHA.109.929364. Epub 2010 Jul 6. Circulation. 2010. PMID: 20606119 Free article.
771 results