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Recoding structural glycoprotein E2 in classical swine fever virus (CSFV) produces complete virus attenuation in swine and protects infected animals against disease.
Velazquez-Salinas L, Risatti GR, Holinka LG, O'Donnell V, Carlson J, Alfano M, Rodriguez LL, Carrillo C, Gladue DP, Borca MV. Velazquez-Salinas L, et al. Among authors: carlson j. Virology. 2016 Jul;494:178-89. doi: 10.1016/j.virol.2016.04.007. Epub 2016 Apr 26. Virology. 2016. PMID: 27110709 Free article.
African Swine Fever Virus Georgia 2007 with a Deletion of Virulence-Associated Gene 9GL (B119L), when Administered at Low Doses, Leads to Virus Attenuation in Swine and Induces an Effective Protection against Homologous Challenge.
O'Donnell V, Holinka LG, Krug PW, Gladue DP, Carlson J, Sanford B, Alfano M, Kramer E, Lu Z, Arzt J, Reese B, Carrillo C, Risatti GR, Borca MV. O'Donnell V, et al. Among authors: carlson j. J Virol. 2015 Aug;89(16):8556-66. doi: 10.1128/JVI.00969-15. Epub 2015 Jun 10. J Virol. 2015. PMID: 26063424 Free PMC article.
African swine fever virus Georgia isolate harboring deletions of 9GL and MGF360/505 genes is highly attenuated in swine but does not confer protection against parental virus challenge.
O'Donnell V, Holinka LG, Sanford B, Krug PW, Carlson J, Pacheco JM, Reese B, Risatti GR, Gladue DP, Borca MV. O'Donnell V, et al. Among authors: carlson j. Virus Res. 2016 Aug 2;221:8-14. doi: 10.1016/j.virusres.2016.05.014. Epub 2016 May 12. Virus Res. 2016. PMID: 27182007
Simultaneous Deletion of the 9GL and UK Genes from the African Swine Fever Virus Georgia 2007 Isolate Offers Increased Safety and Protection against Homologous Challenge.
O'Donnell V, Risatti GR, Holinka LG, Krug PW, Carlson J, Velazquez-Salinas L, Azzinaro PA, Gladue DP, Borca MV. O'Donnell V, et al. Among authors: carlson j. J Virol. 2016 Dec 16;91(1):e01760-16. doi: 10.1128/JVI.01760-16. Print 2017 Jan 1. J Virol. 2016. PMID: 27795430 Free PMC article.
Classical Swine Fever-An Updated Review.
Blome S, Staubach C, Henke J, Carlson J, Beer M. Blome S, et al. Among authors: carlson j. Viruses. 2017 Apr 21;9(4):86. doi: 10.3390/v9040086. Viruses. 2017. PMID: 28430168 Free PMC article. Review.
3,627 results