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An FDA/CDER perspective on nonclinical testing strategies: Classical toxicology approaches and new approach methodologies (NAMs).
Avila AM, Bebenek I, Bonzo JA, Bourcier T, Davis Bruno KL, Carlson DB, Dubinion J, Elayan I, Harrouk W, Lee SL, Mendrick DL, Merrill JC, Peretz J, Place E, Saulnier M, Wange RL, Yao J, Zhao D, Brown PC. Avila AM, et al. Among authors: carlson db. Regul Toxicol Pharmacol. 2020 Jul;114:104662. doi: 10.1016/j.yrtph.2020.104662. Epub 2020 Apr 20. Regul Toxicol Pharmacol. 2020. PMID: 32325112
Approaches to establish thresholds for major food allergens and for gluten in food.
Buchanan R, Dennis S, Gendel S, Acheson D, Assimon SA, Beru N, Bolger P, Carlson D, Carvajal R, Copp C, Falci K, Garber E, Harden E, Kane R, Kvenberg J, Luccioli S, Park D, Raybourne R, Troxell T, Vierk K; Threshold Working Group. Buchanan R, et al. J Food Prot. 2008 May;71(5):1043-88. doi: 10.4315/0362-028x-71.5.1043. J Food Prot. 2008. PMID: 18522044 Free article. Review. No abstract available.
Fixed-target protein serial microcrystallography with an x-ray free electron laser.
Hunter MS, Segelke B, Messerschmidt M, Williams GJ, Zatsepin NA, Barty A, Benner WH, Carlson DB, Coleman M, Graf A, Hau-Riege SP, Pardini T, Seibert MM, Evans J, Boutet S, Frank M. Hunter MS, et al. Among authors: carlson db. Sci Rep. 2014 Aug 12;4:6026. doi: 10.1038/srep06026. Sci Rep. 2014. PMID: 25113598 Free PMC article.
Femtosecond X-ray diffraction from two-dimensional protein crystals.
Frank M, Carlson DB, Hunter MS, Williams GJ, Messerschmidt M, Zatsepin NA, Barty A, Benner WH, Chu K, Graf AT, Hau-Riege SP, Kirian RA, Padeste C, Pardini T, Pedrini B, Segelke B, Seibert MM, Spence JC, Tsai CJ, Lane SM, Li XD, Schertler G, Boutet S, Coleman M, Evans JE. Frank M, et al. Among authors: carlson db. IUCrJ. 2014 Feb 28;1(Pt 2):95-100. doi: 10.1107/S2052252514001444. eCollection 2014 Mar 1. IUCrJ. 2014. PMID: 25075325 Free PMC article.
Feed restriction, but not l-carnitine infusion, alters the liver transcriptome by inhibiting sterol synthesis and mitochondrial oxidative phosphorylation and increasing gluconeogenesis in mid-lactation dairy cows.
Akbar H, Bionaz M, Carlson DB, Rodriguez-Zas SL, Everts RE, Lewin HA, Drackley JK, Loor JJ. Akbar H, et al. Among authors: carlson db. J Dairy Sci. 2013 Apr;96(4):2201-2213. doi: 10.3168/jds.2012-6036. Epub 2013 Feb 22. J Dairy Sci. 2013. PMID: 23462174 Free article.
44 results