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Micro-fabricated scaffolds lead to efficient remission of diabetes in mice.
Buitinga M, Assen F, Hanegraaf M, Wieringa P, Hilderink J, Moroni L, Truckenmüller R, van Blitterswijk C, Römer GW, Carlotti F, de Koning E, Karperien M, van Apeldoorn A. Buitinga M, et al. Among authors: carlotti f. Biomaterials. 2017 Aug;135:10-22. doi: 10.1016/j.biomaterials.2017.03.031. Epub 2017 Mar 27. Biomaterials. 2017. PMID: 28478326
EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion.
Blanchi B, Taurand M, Colace C, Thomaidou S, Audeoud C, Fantuzzi F, Sawatani T, Gheibi S, Sabadell-Basallote J, Boot FWJ, Chantier T, Piet A, Cavanihac C, Pilette M, Balguerie A, Olleik H, Carlotti F, Ejarque M, Fex M, Mulder H, Cnop M, Eizirik DL, Jouannot O, Gaffuri AL, Czernichow P, Zaldumbide A, Scharfmann R, Ravassard P. Blanchi B, et al. Among authors: carlotti f. Mol Metab. 2023 Oct;76:101772. doi: 10.1016/j.molmet.2023.101772. Epub 2023 Jul 11. Mol Metab. 2023. PMID: 37442376 Free PMC article.
β-Cell Generation: Can Rodent Studies Be Translated to Humans?
Carlotti F, Zaldumbide A, Ellenbroek JH, Spijker HS, Hoeben RC, de Koning EJ. Carlotti F, et al. J Transplant. 2011;2011:892453. doi: 10.1155/2011/892453. Epub 2011 Oct 5. J Transplant. 2011. PMID: 22007286 Free PMC article.
Conversion of mature human β-cells into glucagon-producing α-cells.
Spijker HS, Ravelli RB, Mommaas-Kienhuis AM, van Apeldoorn AA, Engelse MA, Zaldumbide A, Bonner-Weir S, Rabelink TJ, Hoeben RC, Clevers H, Mummery CL, Carlotti F, de Koning EJ. Spijker HS, et al. Among authors: carlotti f. Diabetes. 2013 Jul;62(7):2471-80. doi: 10.2337/db12-1001. Epub 2013 Apr 8. Diabetes. 2013. PMID: 23569174 Free PMC article.
The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway.
't Hart LM, Fritsche A, Nijpels G, van Leeuwen N, Donnelly LA, Dekker JM, Alssema M, Fadista J, Carlotti F, Gjesing AP, Palmer CN, van Haeften TW, Herzberg-Schäfer SA, Simonis-Bik AM, Houwing-Duistermaat JJ, Helmer Q, Deelen J, Guigas B, Hansen T, Machicao F, Willemsen G, Heine RJ, Kramer MH, Holst JJ, de Koning EJ, Häring HU, Pedersen O, Groop L, de Geus EJ, Slagboom PE, Boomsma DI, Eekhoff EM, Pearson ER, Diamant M. 't Hart LM, et al. Among authors: carlotti f. Diabetes. 2013 Sep;62(9):3275-81. doi: 10.2337/db13-0227. Epub 2013 May 14. Diabetes. 2013. PMID: 23674605 Free PMC article. Clinical Trial.
89 results