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A novel process driving Alzheimer's disease validated in a mouse model: Therapeutic potential.
Greenfield SA, Cole GM, Coen CW, Frautschy S, Singh RP, Mekkittikul M, Garcia-Ratés S, Morrill P, Hollings O, Passmore M, Hasan S, Carty N, Bison S, Piccoli L, Carletti R, Tacconi S, Chalidou A, Pedercini M, Kroecher T, Astner H, Gerrard PA. Greenfield SA, et al. Among authors: carletti r. Alzheimers Dement (N Y). 2022 Apr 5;8(1):e12274. doi: 10.1002/trc2.12274. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35415206 Free PMC article.
Receptor distribution studies.
Carletti R, Tacconi S, Mugnaini M, Gerrard P. Carletti R, et al. Curr Opin Pharmacol. 2017 Aug;35:94-100. doi: 10.1016/j.coph.2017.07.008. Epub 2017 Aug 10. Curr Opin Pharmacol. 2017. PMID: 28803835 Review.
Identification, biological characterization and pharmacophoric analysis of a new potent and selective NK1 receptor antagonist clinical candidate.
Di Fabio R, Alvaro G, Braggio S, Carletti R, Gerrard PA, Griffante C, Marchioro C, Pozzan A, Melotto S, Poffe A, Piccoli L, Ratti E, Tranquillini E, Trower M, Spada S, Corsi M. Di Fabio R, et al. Among authors: carletti r. Bioorg Med Chem. 2013 Nov 1;21(21):6264-73. doi: 10.1016/j.bmc.2013.09.001. Epub 2013 Sep 11. Bioorg Med Chem. 2013. PMID: 24075145
Novel spirotetracyclic zwitterionic dual H(1)/5-HT(2A) receptor antagonists for the treatment of sleep disorders.
Gianotti M, Botta M, Brough S, Carletti R, Castiglioni E, Corti C, Dal-Cin M, Delle Fratte S, Korajac D, Lovric M, Merlo G, Mesic M, Pavone F, Piccoli L, Rast S, Roscic M, Sava A, Smehil M, Stasi L, Togninelli A, Wigglesworth MJ. Gianotti M, et al. Among authors: carletti r. J Med Chem. 2010 Nov 11;53(21):7778-95. doi: 10.1021/jm100856p. J Med Chem. 2010. PMID: 20942472
99 results