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A recombinant Leishmania amastigote-specific protein, rLiHyG, with adjuvants, protects against infection with Leishmania infantum.
Machado AS, Lage DP, Vale DL, Freitas CS, Linhares FP, Cardoso JMO, Pereira IAG, Ramos FF, Tavares GSV, Ludolf F, Oliveira-da-Silva JA, Bandeira RS, Simões AC, Duarte MC, Oliveira JS, Christodoulides M, Chávez-Fumagalli MA, Roatt BM, Martins VT, Coelho EAF. Machado AS, et al. Among authors: cardoso jmo. Acta Trop. 2022 Jun;230:106412. doi: 10.1016/j.actatropica.2022.106412. Epub 2022 Mar 16. Acta Trop. 2022. PMID: 35305943
Recombinant guanosine-5'-triphosphate (GTP)-binding protein associated with Poloxamer 407-based polymeric micelles protects against Leishmania infantum infection.
Lage DP, Machado AS, Vale DL, Freitas CS, Linhares FP, Cardoso JMO, Pereira IAG, Ramos FF, Tavares GSV, Ludolf F, Oliveira-da-Silva JA, Bandeira RS, Silva AM, Simões LC, Reis TAR, Oliveira JS, Christodoulides M, Chávez-Fumagalli MA, Roatt BM, Martins VT, Coelho EAF. Lage DP, et al. Among authors: cardoso jmo. Cytokine. 2022 May;153:155865. doi: 10.1016/j.cyto.2022.155865. Epub 2022 Mar 23. Cytokine. 2022. PMID: 35339043
Leishmania LiHyC protein is immunogenic and induces protection against visceral leishmaniasis.
Machado AS, Lage DP, Vale DL, Freitas CS, Linhares FP, Cardoso JMO, Oliveira-da-Silva JA, Pereira IAG, Ramos FF, Tavares GSV, Ludolf F, Bandeira RS, Maia LGN, Menezes-Souza D, Duarte MC, Chávez-Fumagalli MA, Roatt BM, Christodoulides M, Martins VT, Coelho EAF. Machado AS, et al. Among authors: cardoso jmo. Parasite Immunol. 2022 Aug;44(8):e12921. doi: 10.1111/pim.12921. Epub 2022 Apr 27. Parasite Immunol. 2022. PMID: 35437797
A Recombinant Chimeric Protein-Based Vaccine Containing T-Cell Epitopes from Amastigote Proteins and Combined with Distinct Adjuvants, Induces Immunogenicity and Protection against Leishmania infantum Infection.
Lage DP, Vale DL, Linhares FP, Freitas CS, Machado AS, Cardoso JMO, de Oliveira D, Galvani NC, de Oliveira MP, Oliveira-da-Silva JA, Ramos FF, Tavares GSV, Ludolf F, Bandeira RS, Pereira IAG, Chávez-Fumagalli MA, Roatt BM, Machado-de-Ávila RA, Christodoulides M, Coelho EAF, Martins VT. Lage DP, et al. Among authors: cardoso jmo. Vaccines (Basel). 2022 Jul 19;10(7):1146. doi: 10.3390/vaccines10071146. Vaccines (Basel). 2022. PMID: 35891310 Free PMC article.
Recombinant endonuclease III protein from Leishmania infantum associated with Th1-type adjuvants is immunogenic and induces protection against visceral leishmaniasis.
Lage DP, Machado AS, Freitas CS, Vale DL, Linhares FP, Cardoso JMO, Oliveira-da-Silva JA, Ramos FF, Pereira IAG, Ludolf F, Tavares GSV, Bandeira RS, Oliveira JS, Menezes-Souza D, Duarte MC, Galdino AS, Christodoulides M, Chávez-Fumagalli MA, Roatt BM, Martins VT, Coelho EAF. Lage DP, et al. Among authors: cardoso jmo. Mol Immunol. 2023 Mar;155:79-90. doi: 10.1016/j.molimm.2023.01.011. Epub 2023 Jan 31. Mol Immunol. 2023. PMID: 36731193
Exploring drug repositioning for leishmaniasis treatment: Ivermectin plus polymeric micelles induce immunological response and protection against tegumentary leishmaniasis.
Freitas CS, Lage DP, Machado AS, Vale DL, Martins VT, Cardoso JMO, Oliveira-da-Silva JA, Reis TAR, Tavares GSV, Ramos FF, Ludolf F, Pereira IAG, Bandeira RS, Fujiwara RT, Bueno LL, Roatt BM, Chávez-Fumagalli MA, Coelho EAF. Freitas CS, et al. Among authors: cardoso jmo. Cytokine. 2023 Apr;164:156143. doi: 10.1016/j.cyto.2023.156143. Epub 2023 Feb 10. Cytokine. 2023. PMID: 36774730
The Use of an Adjuvant System Improves Innate and Adaptive Immune Response When Associated with a Leishmania (Viannia) braziliensis Antigen in a Vaccine Candidate against L. (Leishmania) infantum Infection.
Mathias FAS, Ostolin TLVDP, Reis LES, Cardoso JMO, De Brito RCF, Aguiar Soares RDO, Roatt BM, Vieira PMA, Reis AB. Mathias FAS, et al. Among authors: cardoso jmo. Vaccines (Basel). 2023 Feb 9;11(2):395. doi: 10.3390/vaccines11020395. Vaccines (Basel). 2023. PMID: 36851272 Free PMC article.
Immunoprophylaxis using polypeptide chimera vaccines plus adjuvant system promote Th1 response controlling the spleen parasitism in hamster model of visceral leishmaniasis.
Gusmão MR, Ostolin TLVDP, Carvalho LM, Costa AFP, Moreira GJL, Cardoso JMO, Aguiar-Soares RDO, Reis AB, de Brito RCF, Roatt BM. Gusmão MR, et al. Among authors: cardoso jmo. Vaccine. 2022 Sep 2;40(37):5494-5503. doi: 10.1016/j.vaccine.2022.08.005. Epub 2022 Aug 10. Vaccine. 2022. PMID: 35963820 Free article.
Heterologous vaccine therapy associated with half course of Miltefosine promote activation of the proinflammatory response with control of splenic parasitism in a hamster model of visceral leishmaniasis.
Carvalho LM, Ferreira FC, Gusmão MR, Costa AFP, de Brito RCF, Aguiar-Soares RDO, Reis AB, Cardoso JMO, Carneiro CM, Roatt BM. Carvalho LM, et al. Among authors: cardoso jmo. Curr Res Immunol. 2021 Nov 5;2:194-201. doi: 10.1016/j.crimmu.2021.10.003. eCollection 2021. Curr Res Immunol. 2021. PMID: 35492387 Free PMC article.
24 results