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A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases.
Ghigo A, Murabito A, Sala V, Pisano AR, Bertolini S, Gianotti A, Caci E, Montresor A, Premchandar A, Pirozzi F, Ren K, Della Sala A, Mergiotti M, Richter W, de Poel E, Matthey M, Caldrer S, Cardone RA, Civiletti F, Costamagna A, Quinney NL, Butnarasu C, Visentin S, Ruggiero MR, Baroni S, Crich SG, Ramel D, Laffargue M, Tocchetti CG, Levi R, Conti M, Lu XY, Melotti P, Sorio C, De Rose V, Facchinetti F, Fanelli V, Wenzel D, Fleischmann BK, Mall MA, Beekman J, Laudanna C, Gentzsch M, Lukacs GL, Pedemonte N, Hirsch E. Ghigo A, et al. Among authors: cardone ra. Sci Transl Med. 2022 Mar 30;14(638):eabl6328. doi: 10.1126/scitranslmed.abl6328. Epub 2022 Mar 30. Sci Transl Med. 2022. PMID: 35353541 Free PMC article.
Solid Lipid Nanoparticles Containing Dopamine and Grape Seed Extract: Freeze-Drying with Cryoprotection as a Formulation Strategy to Achieve Nasal Powders.
De Giglio E, Bakowsky U, Engelhardt K, Caponio A, La Pietra M, Cometa S, Castellani S, Guerra L, Fracchiolla G, Poeta ML, Mallamaci R, Cardone RA, Bellucci S, Trapani A. De Giglio E, et al. Among authors: cardone ra. Molecules. 2023 Nov 22;28(23):7706. doi: 10.3390/molecules28237706. Molecules. 2023. PMID: 38067437 Free PMC article.
Combined Dopamine and Grape Seed Extract-Loaded Solid Lipid Nanoparticles: Nasal Mucosa Permeation, and Uptake by Olfactory Ensheathing Cells and Neuronal SH-SY5Y Cells.
Trapani A, Castellani S, Guerra L, De Giglio E, Fracchiolla G, Corbo F, Cioffi N, Passantino G, Poeta ML, Montemurro P, Mallamaci R, Cardone RA, Conese M. Trapani A, et al. Among authors: cardone ra. Pharmaceutics. 2023 Mar 8;15(3):881. doi: 10.3390/pharmaceutics15030881. Pharmaceutics. 2023. PMID: 36986742 Free PMC article.
Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibrosis cells.
Guerra L, Fanelli T, Favia M, Riccardi SM, Busco G, Cardone RA, Carrabino S, Weinman EJ, Reshkin SJ, Conese M, Casavola V. Guerra L, et al. Among authors: cardone ra. J Biol Chem. 2005 Dec 9;280(49):40925-33. doi: 10.1074/jbc.M505103200. Epub 2005 Oct 3. J Biol Chem. 2005. PMID: 16203733 Free article.
Reciprocal protein kinase A regulatory interactions between cystic fibrosis transmembrane conductance regulator and Na+/H+ exchanger isoform 3 in a renal polarized epithelial cell model.
Bagorda A, Guerra L, Di Sole F, Hemle-Kolb C, Cardone RA, Fanelli T, Reshkin SJ, Gisler SM, Murer H, Casavola V. Bagorda A, et al. Among authors: cardone ra. J Biol Chem. 2002 Jun 14;277(24):21480-8. doi: 10.1074/jbc.M112245200. Epub 2002 Apr 5. J Biol Chem. 2002. PMID: 11937500 Free article.
Na+/H+ exchanger regulatory factor 1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del cystic fibrosis transmembrane conductance regulator in human airway CFBE41o- cells.
Favia M, Guerra L, Fanelli T, Cardone RA, Monterisi S, Di Sole F, Castellani S, Chen M, Seidler U, Reshkin SJ, Conese M, Casavola V. Favia M, et al. Among authors: cardone ra. Mol Biol Cell. 2010 Jan 1;21(1):73-86. doi: 10.1091/mbc.e09-03-0185. Epub 2009 Nov 4. Mol Biol Cell. 2010. PMID: 19889841 Free PMC article.
70 results