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Optimized Pyridazinone Nutrient Channel Inhibitors Are Potent and Specific Antimalarial Leads.
Butler MM, Waidyarachchi SL, Shao J, Nguyen ST, Ding X, Cardinale SC, Morin LR, Kwasny SM, Ito M, Gezelle J, Jiménez-Díaz MB, Angulo-Barturen I, Jacobs RT, Burrows JN, Aron ZD, Bowlin TL, Desai SA. Butler MM, et al. Among authors: cardinale sc. Mol Pharmacol. 2022 Sep;102(3):172-182. doi: 10.1124/molpharm.122.000549. Epub 2022 Jul 7. Mol Pharmacol. 2022. PMID: 35798366 Free PMC article.
Identification of a small-molecule entry inhibitor for filoviruses.
Basu A, Li B, Mills DM, Panchal RG, Cardinale SC, Butler MM, Peet NP, Majgier-Baranowska H, Williams JD, Patel I, Moir DT, Bavari S, Ray R, Farzan MR, Rong L, Bowlin TL. Basu A, et al. Among authors: cardinale sc. J Virol. 2011 Apr;85(7):3106-19. doi: 10.1128/JVI.01456-10. Epub 2011 Jan 26. J Virol. 2011. PMID: 21270170 Free PMC article.
Time-dependent botulinum neurotoxin serotype A metalloprotease inhibitors.
Li B, Cardinale SC, Butler MM, Pai R, Nuss JE, Peet NP, Bavari S, Bowlin TL. Li B, et al. Among authors: cardinale sc. Bioorg Med Chem. 2011 Dec 15;19(24):7338-48. doi: 10.1016/j.bmc.2011.10.062. Epub 2011 Oct 26. Bioorg Med Chem. 2011. PMID: 22082667 Free PMC article.
Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions.
Komazin-Meredith G, Chou S, Prichard MN, Hartline CB, Cardinale SC, Comeau K, Williams JD, Khan AR, Peet NP, Bowlin TL. Komazin-Meredith G, et al. Among authors: cardinale sc. Antimicrob Agents Chemother. 2014;58(1):274-8. doi: 10.1128/AAC.01726-13. Epub 2013 Oct 21. Antimicrob Agents Chemother. 2014. PMID: 24145545 Free PMC article.
Small molecule inhibitors of anthrax lethal factor toxin.
Williams JD, Khan AR, Cardinale SC, Butler MM, Bowlin TL, Peet NP. Williams JD, et al. Among authors: cardinale sc. Bioorg Med Chem. 2014 Jan 1;22(1):419-34. doi: 10.1016/j.bmc.2013.11.009. Epub 2013 Nov 13. Bioorg Med Chem. 2014. PMID: 24290062 Free PMC article.
22 results