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Self-delivering RNAi compounds as therapeutic agents in the central nervous system to enhance axonal regeneration after injury.
Woller SA, Ruschel J, Morquette B, Cardia J, Yan D, Holton K, Shmushkovich T, Niederst E, Bulock K, Wolfson A, Abbinanti M, Fournier AE, McKerracher L, Rosen KM. Woller SA, et al. Among authors: cardia j. iScience. 2022 May 10;25(6):104379. doi: 10.1016/j.isci.2022.104379. eCollection 2022 Jun 17. iScience. 2022. PMID: 35620420 Free PMC article.
Visualization of self-delivering hydrophobically modified siRNA cellular internalization.
Ly S, Navaroli DM, Didiot MC, Cardia J, Pandarinathan L, Alterman JF, Fogarty K, Standley C, Lifshitz LM, Bellve KD, Prot M, Echeverria D, Corvera S, Khvorova A. Ly S, et al. Among authors: cardia j. Nucleic Acids Res. 2017 Jan 9;45(1):15-25. doi: 10.1093/nar/gkw1005. Epub 2016 Nov 28. Nucleic Acids Res. 2017. PMID: 27899655 Free PMC article.
Novel hydrophobically modified asymmetric RNAi compounds (sd-rxRNA) demonstrate robust efficacy in the eye.
Byrne M, Tzekov R, Wang Y, Rodgers A, Cardia J, Ford G, Holton K, Pandarinathan L, Lapierre J, Stanney W, Bulock K, Shaw S, Libertine L, Fettes K, Khvorova A, Kaushal S, Pavco P. Byrne M, et al. Among authors: cardia j. J Ocul Pharmacol Ther. 2013 Dec;29(10):855-64. doi: 10.1089/jop.2013.0148. Epub 2013 Nov 1. J Ocul Pharmacol Ther. 2013. PMID: 24180627
Monoalkylglycerol ether lipids promote adipogenesis.
Homan EA, Kim YG, Cardia JP, Saghatelian A. Homan EA, et al. Among authors: cardia jp. J Am Chem Soc. 2011 Apr 13;133(14):5178-81. doi: 10.1021/ja111173c. Epub 2011 Mar 23. J Am Chem Soc. 2011. PMID: 21428285 Free PMC article.
15 results