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Page 1
Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells.
Mensà E, Guescini M, Giuliani A, Bacalini MG, Ramini D, Corleone G, Ferracin M, Fulgenzi G, Graciotti L, Prattichizzo F, Sorci L, Battistelli M, Monsurrò V, Bonfigli AR, Cardelli M, Recchioni R, Marcheselli F, Latini S, Maggio S, Fanelli M, Amatori S, Storci G, Ceriello A, Stocchi V, De Luca M, Magnani L, Rippo MR, Procopio AD, Sala C, Budimir I, Bassi C, Negrini M, Garagnani P, Franceschi C, Sabbatinelli J, Bonafè M, Olivieri F. Mensà E, et al. Among authors: cardelli m. J Extracell Vesicles. 2020 Feb 18;9(1):1725285. doi: 10.1080/20013078.2020.1725285. eCollection 2020. J Extracell Vesicles. 2020. PMID: 32158519 Free PMC article.
A gender--dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity.
Bonafè M, Olivieri F, Cavallone L, Giovagnetti S, Mayegiani F, Cardelli M, Pieri C, Marra M, Antonicelli R, Lisa R, Rizzo MR, Paolisso G, Monti D, Franceschi C. Bonafè M, et al. Among authors: cardelli m. Eur J Immunol. 2001 Aug;31(8):2357-61. doi: 10.1002/1521-4141(200108)31:8<2357::aid-immu2357>3.0.co;2-x. Eur J Immunol. 2001. PMID: 11500818 Free article.
The -174 C/G locus affects in vitro/in vivo IL-6 production during aging.
Olivieri F, Bonafè M, Cavallone L, Giovagnetti S, Marchegiani F, Cardelli M, Mugianesi E, Giampieri C, Moresi R, Stecconi R, Lisa R, Franceschi C. Olivieri F, et al. Among authors: cardelli m. Exp Gerontol. 2002 Jan-Mar;37(2-3):309-14. doi: 10.1016/s0531-5565(01)00197-8. Exp Gerontol. 2002. PMID: 11772517
Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians.
Bonafè M, Marchegiani F, Cardelli M, Olivieri F, Cavallone L, Giovagnetti S, Pieri C, Marra M, Antonicelli R, Troiano L, Gueresi P, Passeri G, Berardelli M, Paolisso G, Barbieri M, Tesei S, Lisa R, De Benedictis G, Franceschi C. Bonafè M, et al. Among authors: cardelli m. Eur J Hum Genet. 2002 May;10(5):292-6. doi: 10.1038/sj.ejhg.5200806. Eur J Hum Genet. 2002. PMID: 12082503
In vitro IL-6 production by EBV-immortalized B lymphocytes from young and elderly people genotyped for -174 C/G polymorphism in IL-6 gene: a model to study the genetic basis of inflamm-aging.
Olivieri F, Bonafè M, Giovagnetti S, Stecconi R, Cardelli M, Cavallone L, Spazzafumo L, Marchegiani F, Carrieri G, Mugianesi E, Giampieri C, Centurelli M, Moresi R, Tesei S, Lisa R, Viticchi C, Falsetti L, Salvioli S, Franceschi C. Olivieri F, et al. Among authors: cardelli m. Mech Ageing Dev. 2003 Apr;124(4):549-53. doi: 10.1016/s0047-6374(03)00035-6. Mech Ageing Dev. 2003. PMID: 12714266
The G/C915 polymorphism of transforming growth factor beta1 is associated with human longevity: a study in Italian centenarians.
Carrieri G, Marzi E, Olivieri F, Marchegiani F, Cavallone L, Cardelli M, Giovagnetti S, Stecconi R, Molendini C, Trapassi C, De Benedictis G, Kletsas D, Franceschi C. Carrieri G, et al. Among authors: cardelli m. Aging Cell. 2004 Dec;3(6):443-8. doi: 10.1111/j.1474-9728.2004.00129.x. Aging Cell. 2004. PMID: 15569360 Free article.
Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians.
Franceschi C, Olivieri F, Marchegiani F, Cardelli M, Cavallone L, Capri M, Salvioli S, Valensin S, De Benedictis G, Di Iorio A, Caruso C, Paolisso G, Monti D. Franceschi C, et al. Among authors: cardelli m. Mech Ageing Dev. 2005 Feb;126(2):351-61. doi: 10.1016/j.mad.2004.08.028. Mech Ageing Dev. 2005. PMID: 15621218 Review.
The interleukin-6 -174 G>C promoter polymorphism is associated with a higher risk of death after an acute coronary syndrome in male elderly patients.
Antonicelli R, Olivieri F, Bonafè M, Cavallone L, Spazzafumo L, Marchegiani F, Cardelli M, Recanatini A, Testarmata P, Boemi M, Parati G, Franceschi C. Antonicelli R, et al. Among authors: cardelli m. Int J Cardiol. 2005 Sep 1;103(3):266-71. doi: 10.1016/j.ijcard.2004.08.064. Int J Cardiol. 2005. PMID: 16098388
90 results