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An automated Design-Build-Test-Learn pipeline for enhanced microbial production of fine chemicals.
Carbonell P, Jervis AJ, Robinson CJ, Yan C, Dunstan M, Swainston N, Vinaixa M, Hollywood KA, Currin A, Rattray NJW, Taylor S, Spiess R, Sung R, Williams AR, Fellows D, Stanford NJ, Mulherin P, Le Feuvre R, Barran P, Goodacre R, Turner NJ, Goble C, Chen GG, Kell DB, Micklefield J, Breitling R, Takano E, Faulon JL, Scrutton NS. Carbonell P, et al. Commun Biol. 2018 Jun 8;1:66. doi: 10.1038/s42003-018-0076-9. eCollection 2018. Commun Biol. 2018. PMID: 30271948 Free PMC article.
SYNBIOCHEM-a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals.
Carbonell P, Currin A, Dunstan M, Fellows D, Jervis A, Rattray NJ, Robinson CJ, Swainston N, Vinaixa M, Williams A, Yan C, Barran P, Breitling R, Chen GG, Faulon JL, Goble C, Goodacre R, Kell DB, Feuvre RL, Micklefield J, Scrutton NS, Shapira P, Takano E, Turner NJ. Carbonell P, et al. Biochem Soc Trans. 2016 Jun 15;44(3):675-7. doi: 10.1042/BST20160009. Biochem Soc Trans. 2016. PMID: 27284023 Free PMC article.
Semisupervised Gaussian Process for Automated Enzyme Search.
Mellor J, Grigoras I, Carbonell P, Faulon JL. Mellor J, et al. Among authors: carbonell p. ACS Synth Biol. 2016 Jun 17;5(6):518-28. doi: 10.1021/acssynbio.5b00294. Epub 2016 Mar 30. ACS Synth Biol. 2016. PMID: 27007080
biochem4j: Integrated and extensible biochemical knowledge through graph databases.
Swainston N, Batista-Navarro R, Carbonell P, Dobson PD, Dunstan M, Jervis AJ, Vinaixa M, Williams AR, Ananiadou S, Faulon JL, Mendes P, Kell DB, Scrutton NS, Breitling R. Swainston N, et al. Among authors: carbonell p. PLoS One. 2017 Jul 14;12(7):e0179130. doi: 10.1371/journal.pone.0179130. eCollection 2017. PLoS One. 2017. PMID: 28708831 Free PMC article.
Highly multiplexed, fast and accurate nanopore sequencing for verification of synthetic DNA constructs and sequence libraries.
Currin A, Swainston N, Dunstan MS, Jervis AJ, Mulherin P, Robinson CJ, Taylor S, Carbonell P, Hollywood KA, Yan C, Takano E, Scrutton NS, Breitling R. Currin A, et al. Among authors: carbonell p. Synth Biol (Oxf). 2019 Oct 29;4(1):ysz025. doi: 10.1093/synbio/ysz025. eCollection 2019. Synth Biol (Oxf). 2019. PMID: 32995546 Free PMC article.
Engineering Escherichia coli towards de novo production of gatekeeper (2S)-flavanones: naringenin, pinocembrin, eriodictyol and homoeriodictyol.
Dunstan MS, Robinson CJ, Jervis AJ, Yan C, Carbonell P, Hollywood KA, Currin A, Swainston N, Feuvre RL, Micklefield J, Faulon JL, Breitling R, Turner N, Takano E, Scrutton NS. Dunstan MS, et al. Among authors: carbonell p. Synth Biol (Oxf). 2020 Aug 6;5(1):ysaa012. doi: 10.1093/synbio/ysaa012. eCollection 2020. Synth Biol (Oxf). 2020. PMID: 33195815 Free PMC article.
150 results