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The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.
Pfefferle S, Schöpf J, Kögl M, Friedel CC, Müller MA, Carbajo-Lozoya J, Stellberger T, von Dall'Armi E, Herzog P, Kallies S, Niemeyer D, Ditt V, Kuri T, Züst R, Pumpor K, Hilgenfeld R, Schwarz F, Zimmer R, Steffen I, Weber F, Thiel V, Herrler G, Thiel HJ, Schwegmann-Wessels C, Pöhlmann S, Haas J, Drosten C, von Brunn A. Pfefferle S, et al. PLoS Pathog. 2011 Oct;7(10):e1002331. doi: 10.1371/journal.ppat.1002331. Epub 2011 Oct 27. PLoS Pathog. 2011. PMID: 22046132 Free PMC article.
Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir.
Carbajo-Lozoya J, Ma-Lauer Y, Malešević M, Theuerkorn M, Kahlert V, Prell E, von Brunn B, Muth D, Baumert TF, Drosten C, Fischer G, von Brunn A. Carbajo-Lozoya J, et al. Virus Res. 2014 May 12;184:44-53. doi: 10.1016/j.virusres.2014.02.010. Epub 2014 Feb 22. Virus Res. 2014. PMID: 24566223 Free PMC article.
p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1.
Ma-Lauer Y, Carbajo-Lozoya J, Hein MY, Müller MA, Deng W, Lei J, Meyer B, Kusov Y, von Brunn B, Bairad DR, Hünten S, Drosten C, Hermeking H, Leonhardt H, Mann M, Hilgenfeld R, von Brunn A. Ma-Lauer Y, et al. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5192-201. doi: 10.1073/pnas.1603435113. Epub 2016 Aug 12. Proc Natl Acad Sci U S A. 2016. PMID: 27519799 Free PMC article.
STAT1 regulates macrophage number and phenotype and prevents renal fibrosis after ischemia-reperfusion injury.
Kemmner S, Bachmann Q, Steiger S, Lorenz G, Honarpisheh M, Foresto-Neto O, Wang S, Carbajo-Lozoya J, Alt V, Schulte C, Chmielewski S, Bluyssen HAR, Heemann U, Baumann M, Lech M, Schmaderer C. Kemmner S, et al. Among authors: carbajo lozoya j. Am J Physiol Renal Physiol. 2019 Feb 1;316(2):F277-F291. doi: 10.1152/ajprenal.00004.2018. Epub 2018 Nov 7. Am J Physiol Renal Physiol. 2019. PMID: 30403164 Free article.
Acetate-free, citrate-acidified bicarbonate dialysis improves serum calcification propensity-a preliminary study.
Lorenz G, Mayer CC, Bachmann Q, Stryeck S, Braunisch MC, Haller B, Carbajo-Lozoya J, Schmidt A, Witthauer S, Abuzahu J, Kemmner S, Angermann S, Koneru N, Wassertheurer S, Bieber R, Heemann U, Madl T, Pasch A, Schmaderer C. Lorenz G, et al. Among authors: carbajo lozoya j. Nephrol Dial Transplant. 2018 Nov 1;33(11):2043-2051. doi: 10.1093/ndt/gfy134. Nephrol Dial Transplant. 2018. PMID: 29860419
Impaired Retinal Vessel Dilation Predicts Mortality in End-Stage Renal Disease.
Günthner R, Hanssen H, Hauser C, Angermann S, Lorenz G, Kemmner S, Matschkal J, Braunisch MC, Kuechle C, Renders L, Moog P, Wassertheurer S, Baumann M, Hammes HP, Mayer CC, Haller B, Stryeck S, Madl T, Carbajo-Lozoya J, Heemann U, Kotliar K, Schmaderer C. Günthner R, et al. Among authors: carbajo lozoya j. Circ Res. 2019 Apr 1. doi: 10.1161/CIRCRESAHA.118.314318. Online ahead of print. Circ Res. 2019. PMID: 30929571
IFN Regulatory Factor 4 Controls Post-ischemic Inflammation and Prevents Chronic Kidney Disease.
Lorenz G, Moschovaki-Filippidou F, Würf V, Metzger P, Steiger S, Batz F, Carbajo-Lozoya J, Koziel J, Schnurr M, Cohen CD, Schmaderer C, Anders HJ, Lindenmeyer M, Lech M. Lorenz G, et al. Among authors: carbajo lozoya j. Front Immunol. 2019 Oct 1;10:2162. doi: 10.3389/fimmu.2019.02162. eCollection 2019. Front Immunol. 2019. PMID: 31632388 Free PMC article.
17 results